Tbp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbp
TATA box binding protein
MGI:101838

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbp^tm1.1Ees/Tbp⁺ B6.129X1(Cg)-Tbp^tm1.1Ees	embryonic lethality during organogenesis, incomplete penetrance	J:77714
Tbp^tm1.1Ees/Tbp⁺ B6.129X1(Cg)-Tbp^tm1.1Ees	fetal growth retardation	J:77714
Tbp^tm1.1Ees/Tbp^tm1.1Ees B6.129X1(Cg)-Tbp^tm1.1Ees	abnormal blood coagulation	J:77714
	embryonic lethality during organogenesis, incomplete penetrance	J:77714
	fetal growth retardation	J:77714
	hemophagocytosis	J:77714
	placenta hemorrhage	J:77714
	postnatal lethality, incomplete penetrance	J:77714
Tbp^tm1Idvd/Tbp^tm1Idvd involves: C57BL/6	embryonic growth arrest	J:79959
Tbp^tm1Idvd/Tbp^tm1Idvd involves: C57BL/6	embryonic lethality at implantation, complete penetrance	J:79959
Tbp^tm1Xjl/Tbp⁺ Tg(CAG-cre/Esr1)5Amc/0 involves: 129S/SvEv C57BL/6 * CBA	abnormal gait	J:213011
	abnormal Purkinje cell dendrite morphology	J:213011
	decreased body weight	J:213011
	impaired balance	J:213011
	impaired coordination	J:213011
	kyphosis	J:213011
	premature death	J:213011
	Purkinje cell degeneration	J:213011
	short stride length	J:213011
	thin cerebellar molecular layer	J:213011
Tbp^tm1Xjl/Tbp^tm1Xjl Tg(Nes-cre)1Kln/? involves: 129S/SvEv * C57BL/6 * SJL	abnormal nest building behavior	J:221703
	cerebellum hypoplasia	J:221703
	decreased body size	J:221703
	decreased locomotor activity	J:221703
	hunched posture	J:221703
	impaired coordination	J:221703
	slow postnatal weight gain	J:221703

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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