F2r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2r
coagulation factor II thrombin receptor
MGI:101802

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2r^tm1.1Cgh/F2r^tm1.1Cgh F2rl1^tm2Cgh/F2rl1^tm2Cgh Tg(Tek-F2r)1Cgh/0 involves: 129S4/SvJae * C57BL/6	normal cardiovascular system phenotype	J:157446
	exencephaly	J:157446
	normal mortality/aging	J:157446
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae	abnormal neural tube morphology	J:188121
	curly tail	J:188121
	spina bifida	J:188121
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae * C57BL/6	decreased survivor rate	J:132733
	embryonic lethality, incomplete penetrance	J:132733
	increased susceptibility to endotoxin shock	J:132733
	increased susceptibility to induced morbidity/mortality	J:132733
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh F2rl3^tm1Cgh/F2rl3^tm1Cgh involves: 129S4/SvJae * C57BL/6	embryonic lethality	J:132733
F2r^tm1Ajc/F2r^tm1Ajc F5^tm1Dgi/F5^tm1Dgi B6.Cg-F5^tm1Dgi F2r^tm1Ajc	decreased embryo size	J:71309
	embryonic lethality, complete penetrance	J:71309
	hemopericardium	J:71309
	hemorrhage	J:71309
	pericardial effusion	J:71309
F2r^tm1Ajc/F2r^tm1Ajc St14^tm1Bug/St14^tm1Bug involves: 129P2/OlaHsd * 129S4/SvJae	normal embryo phenotype	J:188121
	normal mortality/aging	J:188121
F2r^tm1Pago/F2r^tm1Pago F3^tm1.1Dwr/F3^tm1.1Dwr B6.129-F3^tm1.1Dwr F2r^tm1Pago	abnormal induced retina neovascularization	J:135087
F2r^tm1Pago/F2r^tm1Pago Tg(MMTV-PyVT)634Mul/0 B6.Cg-F2r^tm1Pago Tg(MMTV-PyVT)634Mul	increased adenoma incidence	J:138924
	increased mammary adenocarcinoma incidence	J:138924
F2r^tm2Cgh/F2r⁺ F2rl1^tm2Cgh/F2rl1⁺ involves: 129S4/SvJae * C57BL/6	incomplete rostral neuropore closure	J:157446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23