GO Annotations Graph

• Symbol: Tgm3
• Name: transglutaminase 3, E polypeptide
• ID: MGI:98732

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	ISS	J:12602
Molecular Function	GO:0003824	catalytic activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	ISS	J:12602
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	ISO	J:164563
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	IBA	J:265628
Molecular Function	GO:0005198	structural molecule activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0001533	cornified envelope	TAS	J:100385
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0043163	cell envelope organization	ISO	J:164563
Biological Process	GO:0008544	epidermis development	TAS	J:100385
Biological Process	GO:0035315	hair cell differentiation	TAS	J:100385
Biological Process	GO:0031424	keratinization	IEA	J:60000
Biological Process	GO:0018149	peptide cross-linking	ISO	J:164563
Biological Process	GO:0018149	peptide cross-linking	TAS	J:100385
Biological Process	GO:0018149	peptide cross-linking	IBA	J:265628
Biological Process	GO:0043588	skin development	TAS	J:100385