GO Annotations Graph

• Symbol: Snai1
• Name: snail family zinc finger 1
• ID: MGI:98330

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:86131
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:119938
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:183217
Molecular Function	GO:0005515	protein binding	IPI	J:184115
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:86131
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:48573
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:84387
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756452
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9759738
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9759753
Cellular Component	GO:0005634	nucleus	IDA	J:165329
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:84387
Cellular Component	GO:0005634	nucleus	IDA	J:97750
Cellular Component	GO:0005634	nucleus	IDA	J:128085
Cellular Component	GO:0005721	pericentric heterochromatin	ISO	J:164563
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:206163
Biological Process	GO:0060536	cartilage morphogenesis	IGI	J:121243
Biological Process	GO:0010631	epithelial cell migration	IGI	J:121243
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:177252
Biological Process	GO:0001837	epithelial to mesenchymal transition	IDA	J:60189
Biological Process	GO:0001837	epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:72861
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IGI	J:139512
Biological Process	GO:0031069	hair follicle morphogenesis	IDA	J:97750
Biological Process	GO:0070828	heterochromatin organization	IMP	J:206163
Biological Process	GO:0060972	left/right pattern formation	IMP	J:111702
Biological Process	GO:0007498	mesoderm development	IMP	J:111702
Biological Process	GO:0001707	mesoderm formation	IMP	J:72861
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	IDA	J:48573
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:60189
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:84387
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:84387
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:60189
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:86131
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:48573
Biological Process	GO:0010957	negative regulation of vitamin D biosynthetic process	ISO	J:164563
Biological Process	GO:0061314	Notch signaling involved in heart development	IGI	J:165329
Biological Process	GO:0030335	positive regulation of cell migration	IMP	J:165329
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:84387
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IMP	J:206163
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IMP	J:165329
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:48573
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:48573
Biological Process	GO:0060021	roof of mouth development	IGI	J:121243
Biological Process	GO:0060707	trophoblast giant cell differentiation	IDA	J:48573