Msx1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Msx1
msh homeobox 1
MGI:97168

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:236231
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:178676
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:161903
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:32834
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP	J:32834
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:91568
Molecular Function	GO:0005515	protein binding	IPI	J:143687
Molecular Function	GO:0005515	protein binding	IPI	J:49807
Molecular Function	GO:0005515	protein binding	IPI	J:117610
Molecular Function	GO:0005515	protein binding	IPI	J:117610
Molecular Function	GO:0005515	protein binding	IPI	J:158858
Molecular Function	GO:0005515	protein binding	IPI	J:98478
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IMP	J:32834
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:18300
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:43787
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:91568
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:35778
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IGI	J:158858
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:161903
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:161903
Biological Process	GO:0090427	activation of meiosis	IGI	J:178676
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:171190
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:138713
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:124119
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:157031
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:139946
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	IGI	J:139946
Biological Process	GO:0060349	bone morphogenesis	IMP	J:103159
Biological Process	GO:0060349	bone morphogenesis	IMP	J:104286
Biological Process	GO:0060349	bone morphogenesis	IGI	J:125119
Biological Process	GO:0051216	cartilage development	ISO	J:155856
Biological Process	GO:0060536	cartilage morphogenesis	IMP	J:103159
Biological Process	GO:0000902	cell morphogenesis	ISO	J:164563
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IGI	J:171190
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:171190
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:171190
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:171190
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:171190
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:171190
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:150759
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:150759
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:98917
Biological Process	GO:0048598	embryonic morphogenesis	IBA	J:265628
Biological Process	GO:0035880	embryonic nail plate morphogenesis	ISO	J:164563
Biological Process	GO:0035880	embryonic nail plate morphogenesis	IMP	J:114410
Biological Process	GO:0035880	embryonic nail plate morphogenesis	IGI	J:171190
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:156074
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IGI	J:139946
Biological Process	GO:0060325	face morphogenesis	ISO	J:164563
Biological Process	GO:0060325	face morphogenesis	IMP	J:114410
Biological Process	GO:0060325	face morphogenesis	IMP	J:104286
Biological Process	GO:0060325	face morphogenesis	IGI	J:160264
Biological Process	GO:0030900	forebrain development	IMP	J:104935
Biological Process	GO:0030900	forebrain development	IMP	J:91214
Biological Process	GO:0007507	heart development	IGI	J:124119
Biological Process	GO:0007507	heart development	IGI	J:124119
Biological Process	GO:0003007	heart morphogenesis	IGI	J:124119
Biological Process	GO:0001701	in utero embryonic development	IMP	J:124119
Biological Process	GO:0061180	mammary gland epithelium development	IGI	J:61509
Biological Process	GO:0097152	mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:0097152	mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:0097152	mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:0097152	mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:0010463	mesenchymal cell proliferation	IMP	J:156074
Biological Process	GO:0030901	midbrain development	IMP	J:91214
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:104286
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007517	muscle organ development	IPI	J:91568
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:124119
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:124119
Biological Process	GO:0043392	negative regulation of DNA binding	IDA	J:117610
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:91568
Biological Process	GO:0051154	negative regulation of striated muscle cell differentiation	IDA	J:158858
Biological Process	GO:0051154	negative regulation of striated muscle cell differentiation	IGI	J:158858
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:32834
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:91568
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:43787
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:101190
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:161903
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:158858
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:158858
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:117610
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	IGI	J:49807
Biological Process	GO:0042476	odontogenesis	IMP	J:156074
Biological Process	GO:0042476	odontogenesis	IGI	J:160264
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:114410
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IGI	J:139946
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:2001055	positive regulation of mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:2001055	positive regulation of mesenchymal cell apoptotic process	IGI	J:150759
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:54600
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:54600
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:36231
Biological Process	GO:0034504	protein localization to nucleus	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0042481	regulation of odontogenesis	IGI	J:160264
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060021	roof of mouth development	IMP	J:104286
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IGI	J:171190
Biological Process	GO:0048863	stem cell differentiation	IGI	J:125119
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:36231
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:36231

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23