GO Annotations Graph

• Symbol: Il5
• Name: interleukin 5
• ID: MGI:96557

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:155856
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IDA	J:62510
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0005137	interleukin-5 receptor binding	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:116306
Cellular Component	GO:0005615	extracellular space	IDA	J:172134
Cellular Component	GO:0005615	extracellular space	IDA	J:91939
Cellular Component	GO:0005615	extracellular space	IDA	J:117165
Cellular Component	GO:0005615	extracellular space	IDA	J:143168
Cellular Component	GO:0005615	extracellular space	IDA	J:91286
Cellular Component	GO:0005615	extracellular space	IDA	J:65439
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0038043	interleukin-5-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:62510
Biological Process	GO:0030890	positive regulation of B cell proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:26926
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:26926
Biological Process	GO:0045645	positive regulation of eosinophil differentiation	ISO	J:155856
Biological Process	GO:0002639	positive regulation of immunoglobulin production	IGI	J:132106
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:62510
Biological Process	GO:0071803	positive regulation of podosome assembly	ISO	J:164563
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	ISO	J:155856