Nr1h3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nr1h3
nuclear receptor subfamily 1, group H, member 3
MGI:1352462

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IMP	J:264834
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210948
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89079
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:154828
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:89079
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:226000
Molecular Function	GO:0005515	protein binding	IPI	J:134888
Molecular Function	GO:0005515	protein binding	IPI	J:142045
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210948
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94492
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89079
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0032810	sterol response element binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154828
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:235724
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IMP	J:235724
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:89079
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	EXP	J:320338
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:154828
Biological Process	GO:0043277	apoptotic cell clearance	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0044255	cellular lipid metabolic process	IDA	J:89079
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:173138
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:123957
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:206917
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:89079
Biological Process	GO:0006633	fatty acid biosynthetic process	TAS	J:65994
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	IMP	J:142844
Biological Process	GO:0055088	lipid homeostasis	IGI	J:123957
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0010887	negative regulation of cholesterol storage	IGI	J:123957
Biological Process	GO:0010887	negative regulation of cholesterol storage	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IGI	J:262347
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:85276
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:173138
Biological Process	GO:0050728	negative regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0032369	negative regulation of lipid transport	ISO	J:164563
Biological Process	GO:0043031	negative regulation of macrophage activation	IDA	J:173138
Biological Process	GO:0090188	negative regulation of pancreatic juice secretion	IMP	J:142844
Biological Process	GO:0048550	negative regulation of pinocytosis	ISO	J:164563
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:142844
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	IDA	J:206173
Biological Process	GO:0090341	negative regulation of secretion of lysosomal enzymes	IMP	J:142844
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:173138
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0036151	phosphatidylcholine acyl-chain remodeling	IMP	J:206173
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:135705
Biological Process	GO:0032376	positive regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:65994
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154828
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:135705
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210948
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:89079
Biological Process	GO:0032570	response to progesterone	ISO	J:164563
Biological Process	GO:0055092	sterol homeostasis	IMP	J:105722
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:105722
Biological Process	GO:0070328	triglyceride homeostasis	IGI	J:123957

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23