GO Annotations Graph

• Symbol: Mixl1
• Name: Mix paired-like homeobox
• ID: MGI:1351322

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:190263
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190288
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190269
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190085
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190085
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190263
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190269
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:190269
Molecular Function	GO:0005515	protein binding	IPI	J:190269
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:190269
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:190269
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:190085
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:190269
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:190263
Cellular Component	GO:0000785	chromatin	IDA	J:190288
Cellular Component	GO:0000785	chromatin	IDA	J:190085
Cellular Component	GO:0000785	chromatin	IDA	J:190269
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9758506
Cellular Component	GO:0005634	nucleus	IDA	J:202591
Cellular Component	GO:0005634	nucleus	IDA	J:131238
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0042074	cell migration involved in gastrulation	IMP	J:117059
Biological Process	GO:0048565	digestive tract development	IMP	J:77443
Biological Process	GO:0007492	endoderm development	IMP	J:77443
Biological Process	GO:0001706	endoderm formation	IBA	J:265628
Biological Process	GO:0001706	endoderm formation	IMP	J:117059
Biological Process	GO:0035987	endodermal cell differentiation	IDA	J:190085
Biological Process	GO:0007369	gastrulation	IMP	J:77443
Biological Process	GO:0007507	heart development	IMP	J:77443
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IDA	J:190288
Biological Process	GO:0030097	hemopoiesis	IDA	J:131238
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	IDA	J:190085
Biological Process	GO:2000382	positive regulation of mesoderm development	IDA	J:190288
Biological Process	GO:2000382	positive regulation of mesoderm development	IDA	J:131238
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190085
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190263
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190288
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190269
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190085
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628