Foxc2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Foxc2
forkhead box C2
MGI:1347481

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	ISS	J:40156
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:33942
Molecular Function	GO:0001216	DNA-binding transcription activator activity	IDA	J:40156
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISO	J:164563
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISS	J:40156
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:131323
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:140365
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:119144
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:131323
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISS	J:40156
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:140365
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0003275	apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:0048844	artery morphogenesis	IMP	J:55316
Biological Process	GO:0048844	artery morphogenesis	IMP	J:57677
Biological Process	GO:0001568	blood vessel development	IGI	J:119144
Biological Process	GO:0097746	blood vessel diameter maintenance	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:71693
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:102130
Biological Process	GO:0043010	camera-type eye development	IMP	J:61775
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:119303
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:39636
Biological Process	GO:0008283	cell population proliferation	IMP	J:55575
Biological Process	GO:0030199	collagen fibril organization	IMP	J:61775
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP	J:39636
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:55316
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IMP	J:55316
Biological Process	GO:0072011	glomerular endothelium development	IMP	J:106710
Biological Process	GO:0072144	glomerular mesangial cell development	IMP	J:106710
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:119303
Biological Process	GO:0007507	heart development	IMP	J:57677
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0003007	heart morphogenesis	IGI	J:119303
Biological Process	GO:0008286	insulin receptor signaling pathway	ISS	J:40156
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:60834
Biological Process	GO:0001945	lymph vessel development	IGI	J:119144
Biological Process	GO:0001946	lymphangiogenesis	ISO	J:164563
Biological Process	GO:0001946	lymphangiogenesis	ISS	J:40156
Biological Process	GO:0001656	metanephros development	IMP	J:106710
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	ISS	J:94144
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:140365
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:71693
Biological Process	GO:0001503	ossification	IMP	J:39636
Biological Process	GO:0048341	paraxial mesoderm formation	IGI	J:71693
Biological Process	GO:0048343	paraxial mesodermal cell fate commitment	IMP	J:39636
Biological Process	GO:0072112	podocyte differentiation	IMP	J:106710
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	IDA	J:140365
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	IDA	J:140365
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISS	J:40156
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:40156
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	IDA	J:140365
Biological Process	GO:0033625	positive regulation of integrin activation	IC	J:140365
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:140365
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:131323
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:119144
Biological Process	GO:0035470	positive regulation of vascular wound healing	IDA	J:140365
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0046620	regulation of organ growth	IGI	J:119303
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009725	response to hormone	ISS	J:40156
Biological Process	GO:0009725	response to hormone	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:55575
Biological Process	GO:0001501	skeletal system development	IGI	J:55575
Biological Process	GO:0001756	somitogenesis	IGI	J:71693
Biological Process	GO:0001657	ureteric bud development	IMP	J:60834
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IGI	J:119303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23