Hnf4a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hnf4a
hepatic nuclear factor 4, alpha
MGI:109128

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050544	arachidonic acid binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:28121
Molecular Function	GO:0003677	DNA binding	IDA	J:94267
Molecular Function	GO:0003677	DNA binding	IDA	J:91695
Molecular Function	GO:0003677	DNA binding	IDA	J:111670
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:249196
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:97364
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:106993
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:28121
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:64004
Molecular Function	GO:0005504	fatty acid binding	ISO	J:155856
Molecular Function	GO:0005504	fatty acid binding	ISO	J:164563
Molecular Function	GO:0000062	fatty-acyl-CoA binding	ISO	J:155856
Molecular Function	GO:0036042	long-chain fatty acyl-CoA binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:156994
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0005515	protein binding	IPI	J:125929
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:188369
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:140378
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:16244
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0070540	stearic acid binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:97364
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:155856
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	IC	J:249196
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-186663
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:28121
Cellular Component	GO:0005634	nucleus	IDA	J:114400
Cellular Component	GO:0005634	nucleus	IDA	J:16244
Cellular Component	GO:0005634	nucleus	IDA	J:44977
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:97579
Cellular Component	GO:0005634	nucleus	IDA	J:106933
Cellular Component	GO:0005634	nucleus	IDA	J:45483
Biological Process	GO:0006637	acyl-CoA metabolic process	ISO	J:155856
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0007596	blood coagulation	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0045216	cell-cell junction organization	ISO	J:155856
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:67396
Biological Process	GO:0007164	establishment of tissue polarity	ISO	J:155856
Biological Process	GO:0042593	glucose homeostasis	IMP	J:97364
Biological Process	GO:0070365	hepatocyte differentiation	IEA	J:72247
Biological Process	GO:0055088	lipid homeostasis	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IMP	J:106993
Biological Process	GO:1902569	negative regulation of activation of Janus kinase activity	ISO	J:155856
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0042308	negative regulation of protein import into nucleus	ISO	J:155856
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	ISO	J:155856
Biological Process	GO:0006591	ornithine metabolic process	ISO	J:164563
Biological Process	GO:0055091	phospholipid homeostasis	IMP	J:67396
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:271712
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:45483
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:249196
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:44977
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045722	positive regulation of gluconeogenesis	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:67396
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:97364
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:106933
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:108479
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94267
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:64004
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:28121
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:125929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:125929
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:283180
Biological Process	GO:0042752	regulation of circadian rhythm	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:38391
Biological Process	GO:0010470	regulation of gastrulation	IMP	J:21129
Biological Process	GO:0050796	regulation of insulin secretion	IMP	J:97364
Biological Process	GO:0019216	regulation of lipid metabolic process	ISO	J:164563
Biological Process	GO:0032534	regulation of microvillus assembly	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:188369
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:188369
Biological Process	GO:0009749	response to glucose	IMP	J:97364
Biological Process	GO:0009749	response to glucose	ISO	J:155856
Biological Process	GO:0035983	response to trichostatin A	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0007548	sex differentiation	IMP	J:129617
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:45399
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:64004
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:67396
Biological Process	GO:0003323	type B pancreatic cell development	IEA	J:72247
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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