Srf GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Srf
serum response factor
MGI:106658

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:171727
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:136678
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IDA	J:169423
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:173014
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:70265
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:173014
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:183657
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:265605
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:265732
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:82578
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:161853
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:36916
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:171727
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:155856
Molecular Function	GO:0070878	primary miRNA binding	IDA	J:224735
Molecular Function	GO:0005515	protein binding	IPI	J:83853
Molecular Function	GO:0005515	protein binding	IPI	J:265732
Molecular Function	GO:0005515	protein binding	IPI	J:150313
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:136678
Molecular Function	GO:0005515	protein binding	IPI	J:180125
Molecular Function	GO:0005515	protein binding	IPI	J:110800
Molecular Function	GO:0005515	protein binding	IPI	J:172496
Molecular Function	GO:0005515	protein binding	IPI	J:69012
Molecular Function	GO:0005515	protein binding	IPI	J:201868
Molecular Function	GO:0005515	protein binding	IPI	J:117610
Molecular Function	GO:0005515	protein binding	IPI	J:144638
Molecular Function	GO:0005515	protein binding	IPI	J:117610
Molecular Function	GO:0005515	protein binding	IPI	J:172496
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:173014
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:82185
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:117610
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:117610
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:69012
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:36916
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:70265
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:161853
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0010736	serum response element binding	IDA	J:265732
Molecular Function	GO:0010736	serum response element binding	ISO	J:164563
Molecular Function	GO:0010736	serum response element binding	IDA	J:265605
Molecular Function	GO:0010736	serum response element binding	IBA	J:265628
Molecular Function	GO:0010736	serum response element binding	IDA	J:34031
Molecular Function	GO:0010736	serum response element binding	IDA	J:34031
Cellular Component	GO:0000785	chromatin	IDA	J:166020
Cellular Component	GO:0005737	cytoplasm	IDA	J:124707
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9620391
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9768835
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IC	J:82578
Cellular Component	GO:0005634	nucleus	IDA	J:101311
Cellular Component	GO:0005634	nucleus	IDA	J:124707
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:265605
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:98409
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:156871
Biological Process	GO:0007015	actin filament organization	IMP	J:140104
Biological Process	GO:0008306	associative learning	IMP	J:110972
Biological Process	GO:0048675	axon extension	IMP	J:209602
Biological Process	GO:0070830	bicellular tight junction assembly	IMP	J:156871
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:140104
Biological Process	GO:0060532	bronchus cartilage development	IMP	J:203056
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	IGI	J:173014
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	ISO	J:164563
Biological Process	GO:0055003	cardiac myofibril assembly	IMP	J:94725
Biological Process	GO:0060947	cardiac vascular smooth muscle cell differentiation	IMP	J:94725
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	IMP	J:140104
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:171452
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:166639
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:171452
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:164524
Biological Process	GO:0090398	cellular senescence	ISO	J:164563
Biological Process	GO:0030038	contractile actin filament bundle assembly	IMP	J:94725
Biological Process	GO:0048589	developmental growth	IMP	J:50876
Biological Process	GO:0035912	dorsal aorta morphogenesis	IMP	J:94725
Biological Process	GO:0090136	epithelial cell-cell adhesion	IMP	J:156871
Biological Process	GO:0010669	epithelial structure maintenance	IMP	J:156871
Biological Process	GO:0048821	erythrocyte development	IMP	J:166639
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:156871
Biological Process	GO:0061029	eyelid development in camera-type eye	IMP	J:156871
Biological Process	GO:0060324	face development	IMP	J:144862
Biological Process	GO:0046847	filopodium assembly	IMP	J:140104
Biological Process	GO:0046847	filopodium assembly	IMP	J:140104
Biological Process	GO:0030900	forebrain development	IMP	J:161853
Biological Process	GO:0007369	gastrulation	IMP	J:50876
Biological Process	GO:0007507	heart development	IMP	J:91025
Biological Process	GO:0007507	heart development	IMP	J:101311
Biological Process	GO:0007507	heart development	IMP	J:101311
Biological Process	GO:0001947	heart looping	IMP	J:101311
Biological Process	GO:0060347	heart trabecula formation	IMP	J:94725
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:166639
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:166639
Biological Process	GO:0021766	hippocampus development	IMP	J:98409
Biological Process	GO:0001701	in utero embryonic development	IMP	J:50876
Biological Process	GO:0002521	leukocyte differentiation	IMP	J:166639
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0060292	long-term synaptic depression	IMP	J:110972
Biological Process	GO:0060425	lung morphogenesis	IMP	J:203056
Biological Process	GO:0061145	lung smooth muscle development	IMP	J:203056
Biological Process	GO:0035855	megakaryocyte development	IMP	J:166639
Biological Process	GO:0035855	megakaryocyte development	IMP	J:164524
Biological Process	GO:0035855	megakaryocyte development	IMP	J:164524
Biological Process	GO:0001707	mesoderm formation	IMP	J:65669
Biological Process	GO:0001707	mesoderm formation	IMP	J:50876
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	IMP	J:156871
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:96122
Biological Process	GO:1900222	negative regulation of amyloid-beta clearance	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:1902894	negative regulation of miRNA transcription	IDA	J:224735
Biological Process	GO:1902894	negative regulation of miRNA transcription	IDA	J:224735
Biological Process	GO:0001764	neuron migration	IMP	J:98409
Biological Process	GO:0031175	neuron projection development	IMP	J:147426
Biological Process	GO:0030168	platelet activation	IMP	J:164524
Biological Process	GO:0030220	platelet formation	IMP	J:166639
Biological Process	GO:0030220	platelet formation	IMP	J:164524
Biological Process	GO:0045773	positive regulation of axon extension	IMP	J:209602
Biological Process	GO:0045773	positive regulation of axon extension	IGI	J:209602
Biological Process	GO:0045773	positive regulation of axon extension	IGI	J:209602
Biological Process	GO:0045597	positive regulation of cell differentiation	ISO	J:73065
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:177245
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:161853
Biological Process	GO:0051491	positive regulation of filopodium assembly	IMP	J:140104
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:224735
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:151625
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	ISO	J:164563
Biological Process	GO:0046016	positive regulation of transcription by glucose	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:173014
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:265732
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:265605
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:151377
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:69012
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:110800
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:36916
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:110800
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:101311
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:121211
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045059	positive thymic T cell selection	IMP	J:169423
Biological Process	GO:0090009	primitive streak formation	IMP	J:50876
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:140104
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:82578
Biological Process	GO:0034097	response to cytokine	ISO	J:164563
Biological Process	GO:0009725	response to hormone	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	IMP	J:94725
Biological Process	GO:0043589	skin morphogenesis	IMP	J:156871
Biological Process	GO:0043149	stress fiber assembly	IMP	J:164524
Biological Process	GO:0043149	stress fiber assembly	IMP	J:164524
Biological Process	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	IMP	J:98409
Biological Process	GO:0048538	thymus development	IMP	J:144862
Biological Process	GO:0030878	thyroid gland development	IMP	J:144862
Biological Process	GO:0060534	trachea cartilage development	IMP	J:203056
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:101311
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:151377
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:151377
Biological Process	GO:0001829	trophectodermal cell differentiation	ISO	J:73065

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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