GO Annotations Graph

• Symbol: Dlx5
• Name: distal-less homeobox 5
• ID: MGI:101926

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:44405
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:196266
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0071837	HMG box domain binding	IPI	J:175179
Molecular Function	GO:0005515	protein binding	IPI	J:67230
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:196266
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:94905
Cellular Component	GO:0000785	chromatin	IDA	J:196266
Cellular Component	GO:0005737	cytoplasm	IDA	J:58233
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9007731
Cellular Component	GO:0005634	nucleus	IDA	J:58233
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IBA	J:265628
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:127939
Biological Process	GO:0007411	axon guidance	IMP	J:124891
Biological Process	GO:0007409	axonogenesis	IMP	J:81736
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:196266
Biological Process	GO:0060349	bone morphogenesis	IMP	J:104286
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0071773	cellular response to BMP stimulus	IMP	J:196266
Biological Process	GO:0043583	ear development	IMP	J:104286
Biological Process	GO:0009790	embryo development	IBA	J:265628
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:77244
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:135784
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:135784
Biological Process	GO:0001958	endochondral ossification	IMP	J:155388
Biological Process	GO:0030855	epithelial cell differentiation	IGI	J:127939
Biological Process	GO:0060325	face morphogenesis	IMP	J:104286
Biological Process	GO:0060322	head development	IGI	J:93183
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:114449
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:78406
Biological Process	GO:0097376	interneuron axon guidance	IMP	J:231786
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0021889	olfactory bulb interneuron differentiation	IMP	J:231786
Biological Process	GO:0060166	olfactory pit development	IMP	J:81736
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0001649	osteoblast differentiation	IDA	J:94905
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:124891
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:94905
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:114449
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:231786
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:122483
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:122483
Biological Process	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	IMP	J:196266
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:78406
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060021	roof of mouth development	IMP	J:104286
Biological Process	GO:0060021	roof of mouth development	IGI	J:122483
Biological Process	GO:0060021	roof of mouth development	IGI	J:122483