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Mir19b-1 Gene Detail
Summary
  • Symbol
    Mir19b-1
  • Name
    microRNA 19b-1
  • Synonyms
    mir 19b-1, Mirn19b-1, mmu-mir-19b-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:3629917
    NCBI Gene: 751527
  • Member of
    Mirc1 cluster
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr14:115281737-115281823 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 59.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629917
 miRNA gene Chr14:115281737-115281823 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008155
 miRNA gene Chr14:112498612-112498698 (+)
A/J MGP_AJ_G0008143
 miRNA gene Chr14:108247169-108247255 (+)
AKR/J MGP_AKRJ_G0008122
 miRNA gene Chr14:111782299-111782385 (+)
BALB/cJ MGP_BALBcJ_G0008126
 miRNA gene Chr14:108764129-108764215 (+)
C3H/HeJ MGP_C3HHeJ_G0008069
 miRNA gene Chr14:111608490-111608576 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008317
 miRNA gene Chr14:116828092-116828178 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007400
 miRNA gene Chr14:104418515-104418601 (+)
CAST/EiJ MGP_CASTEiJ_G0007944
 miRNA gene Chr14:109386296-109386382 (+)
CBA/J MGP_CBAJ_G0008037
 miRNA gene Chr14:121367328-121367414 (+)
DBA/2J MGP_DBA2J_G0008073
 miRNA gene Chr14:108168772-108168858 (+)
FVB/NJ MGP_FVBNJ_G0008097
 miRNA gene Chr14:106514031-106514117 (+)
LP/J MGP_LPJ_G0008153
 miRNA gene Chr14:113526037-113526123 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008064
 miRNA gene Chr14:126245087-126245173 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008312
 miRNA gene Chr14:111208216-111208302 (+)
PWK/PhJ MGP_PWKPhJ_G0007866
 miRNA gene Chr14:105114754-105114840 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007761
 miRNA gene Chr14:107345803-107345889 (+)
WSB/EiJ MGP_WSBEiJ_G0008022
 miRNA gene Chr14:111952540-111952626 (+)



Homology
more
  • Human Ortholog
    MIR19B1, microRNA 19b-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR19B1, microRNA 19b-1
  • Synonyms
    C13orf25, MIR17HG, MIR19B, miR-19b-1, MIRH1, MIRHG1, MIRN19B1, miRNA19B1
  • Links
    NCBI Gene ID: 406980

  • Chr Location
    chr13:91351192-91351278 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Mir19b-1
  • Find Mice (IMSR)
    1 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    75
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    57
  • Literature Summary
    19
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 751527 NCBI Gene Model | MGI Sequence Detail 87 C57BL/6J ±  kb
transcript NR_029815 RefSeq | MGI Sequence Detail 87 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 9
    Primer pair 5
    Other 4
Other Database
Links
less
miRBase MI0000718
References
more
  • Summaries
    All 45
    Developmental Gene Expression 19
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:67314 Roix J, et al., Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14. Genetics. 2001 Feb;157(2):803-15
  • Latest
    J:346342 Taipaleenmaki H, et al., Antagonizing microRNA-19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice. EMBO Mol Med. 2022 Nov 8;14(11):e13617
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory