Mir17 MGI Mouse Gene Detail - MGI:3619065

Symbol

Mir17
Name

microRNA 17
Synonyms

mir 17, Mirn17, mmu-mir-17

Feature Type

miRNA gene
IDs

MGI:3619065
NCBI Gene: 723905
Member of

Mirc1 cluster
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr14:115281103-115281186 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 59.40 cM
Mapping Data

2 experiments

SNPs within 2kb

77 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619065	miRNA gene	Chr14:115281103-115281186 (+)
129S1/SvImJ	ENSMUSG00200024678	miRNA gene	Chr14:104178033-104178116 (+)
A/J	ENSMUSG00195032055	miRNA gene	Chr14:103932661-103932744 (+)
AKR/J	ENSMUSG00220007776	miRNA gene	Chr14:103710628-103710711 (+)
BALB/cJ	ENSMUSG00180028996	miRNA gene	Chr14:103424861-103424944 (+)
C3H/HeJ	ENSMUSG00175005947	miRNA gene	Chr14:105360627-105360710 (+)
C57BL/6NJ	ENSMUSG00215025258	miRNA gene	Chr14:103546346-103546429 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007396	miRNA gene	Chr14:104417894-104417977 (+)
CAST/EiJ	ENSTCUG00005007138	miRNA gene	Chr14:105044998-105045081 (+)
CBA/J	ENSMUSG00210027280	miRNA gene	Chr14:104329315-104329398 (+)
DBA/2J	ENSMUSG00185021610	miRNA gene	Chr14:109485634-109485717 (+)
FVB/NJ	ENSMUSG00205007668	miRNA gene	Chr14:103040493-103040576 (+)
JF1/MsJ	ENSUMUG00000012865	miRNA gene	Chr14:120537262-120537345 (+)
LP/J	ENSMUSG00230001912	miRNA gene	Chr14:121479427-121479510 (+)
NOD/ShiLtJ	ENSMUSG00190027507	miRNA gene	Chr14:104119691-104119774 (+)
NZO/HlLtJ	ENSMUSG00225021553	miRNA gene	Chr14:111482151-111482234 (+)
PWK/PhJ	ENSLUMG00010029149	miRNA gene	Chr14:103389793-103389876 (+)
SPRET/EiJ	ENSMSPG00010012315	miRNA gene	Chr14:107571578-107571661 (+)
WSB/EiJ	ENSIUOG00005031241	miRNA gene	Chr14:103310490-103310573 (+)

Human Ortholog

MIR17, microRNA 17

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR17, microRNA 17
Synonyms

hsa-mir-17, miR-17, miR17-3p, MIR17-5p, MIR91, MIRN17, MIRN91, miRNA17, miRNA91
Links

HGNC:31547

NCBI Gene ID: 406952
Chr Location

chr13:91350605-91350688 (+) GRCh38

MGI Vertebrate Homology

Mir17 stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: MIR17
Gene Tree

Mir17

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Radiation induced

1
Targeted

3
Genomic Mutations

5 involving Mir17
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

61
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

814
Tissues

90
Literature Summary

42

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065508 (Evidence)
NCBI Gene

723905

Representative Sequences				Length	Strain/Species	Flank
	genomic	723905	NCBI Gene Model \| MGI Sequence Detail	84	C57BL/6J	± kb
	transcript	NR_029785	RefSeq \| MGI Sequence Detail	84	C57BL/6

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All nucleic 23

Primer pair 12

Other 11

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miRBase

MI0000687

Summaries

All 115

Developmental Gene Expression 42

Gene Ontology 9

Phenotypes 5
Earliest

J:67314 Roix J, et al., Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14. Genetics. 2001 Feb;157(2):803-15
Latest

J:348657 Badr A, et al., Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease. Brain Behav Immun. 2024 May 7;119:919-944

TSS for Mir17:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr127128	Chr14:115279707-115279719 (+)	-1,390 bp
Tssr127129	Chr14:115280184-115280188 (+)	-917 bp
Tssr127130	Chr14:115280915-115280919 (+)	-186 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24