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Rnase13 Gene Detail
Summary
  • Symbol
    Rnase13
  • Name
    ribonuclease, RNase A family, 13 (non-active)
  • Feature Type
    protein coding gene
  • IDs
    MGI:3528592
    NCBI Gene: 497071
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:52158819-52160230 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.73 cM, cytoband B-C1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3528592
 protein coding gene Chr14:52158817-52160734 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021285
 protein coding gene Chr14:45945179-45945792 (-)
A/J MGP_AJ_G0021242
 protein coding gene Chr14:44749902-44750515 (-)
AKR/J MGP_AKRJ_G0021218
 protein coding gene Chr14:46366256-46366869 (-)
BALB/cJ MGP_BALBcJ_G0021246
 protein coding gene Chr14:44857807-44858420 (-)
C3H/HeJ MGP_C3HHeJ_G0021026
 protein coding gene Chr14:46172106-46172719 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021685
 protein coding gene Chr14:47960053-47960666 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019230
 protein coding gene Chr14:43940769-43941382 (-)
CAST/EiJ MGP_CASTEiJ_G0020545
 protein coding gene Chr14:43135841-43136454 (-)
CBA/J MGP_CBAJ_G0020993
 protein coding gene Chr14:49427955-49428568 (-)
DBA/2J MGP_DBA2J_G0021114
 protein coding gene Chr14:44514992-44515605 (-)
FVB/NJ MGP_FVBNJ_G0021097
 protein coding gene Chr14:44096971-44097584 (-)
LP/J MGP_LPJ_G0021189
 protein coding gene Chr14:46545726-46546339 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021120
 protein coding gene Chr14:48871288-48871901 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021712
 protein coding gene Chr14:45753641-45754254 (-)
PWK/PhJ MGP_PWKPhJ_G0020294
 protein coding gene Chr14:41261335-41261948 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020121
 protein coding gene Chr14:41778890-41779503 (-)
WSB/EiJ MGP_WSBEiJ_G0020598
 protein coding gene Chr14:46053471-46054084 (-)



Homology
more
  • Human Ortholog
    RNASE13, ribonuclease A family member 13 (inactive)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNASE13, ribonuclease A family member 13 (inactive)
  • Synonyms
    HEL-S-86p, RAL1
  • Links
    NCBI Gene ID: 440163
    neXtProt AC: NX_Q5GAN3
    UniProt: Q5GAN3

  • Chr Location
    14q11.2; chr14:21032818-21034807 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice exhibit normal epididymis, sperm, and fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000068392 Ensembl Gene Model | MGI Sequence Detail 1412 C57BL/6J ±  kb
    transcript ENSMUST00000089771 Ensembl | MGI Sequence Detail 1412 Not Applicable  
    polypeptide ENSMUSP00000087203 Ensembl | MGI Sequence Detail 153 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 21
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:95949 Cho S, et al., The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Genomics. 2005 Feb;85(2):208-20
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory