About   Help   FAQ
Rasl10b Gene Detail
Summary
  • Symbol
    Rasl10b
  • Name
    RAS-like, family 10, member B
  • Synonyms
    B230331P10Rik, VTS58635
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685575
    NCBI Gene: 276952
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83299963-83311865 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 50.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    317 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685575
 protein coding gene Chr11:83299963-83311865 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018846
 protein coding gene Chr11:84730450-84742323 (+)
A/J MGP_AJ_G0018813
 protein coding gene Chr11:81519269-81531142 (+)
AKR/J MGP_AKRJ_G0018783
 protein coding gene Chr11:83944660-83956533 (+)
BALB/cJ MGP_BALBcJ_G0018786
 protein coding gene Chr11:81930589-81942491 (+)
C3H/HeJ MGP_C3HHeJ_G0018600
 protein coding gene Chr11:84004497-84016370 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019238
 protein coding gene Chr11:87329660-87341562 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016872
 protein coding gene Chr11:78645700-78657421 (+)
CAST/EiJ MGP_CASTEiJ_G0018155
 protein coding gene Chr11:84581296-84592585 (+)
CBA/J MGP_CBAJ_G0018571
 protein coding gene Chr11:91103508-91115381 (+)
DBA/2J MGP_DBA2J_G0018679
 protein coding gene Chr11:81115573-81127666 (+)
FVB/NJ MGP_FVBNJ_G0018668
 protein coding gene Chr11:80598296-80610198 (+)
LP/J MGP_LPJ_G0018749
 protein coding gene Chr11:85296457-85308330 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018695
 protein coding gene Chr11:91271878-91283780 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019278
 protein coding gene Chr11:84213231-84225108 (+)
PWK/PhJ MGP_PWKPhJ_G0017924
 protein coding gene Chr11:81875172-81887155 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017716
 protein coding gene Chr11:83752331-83764217 (+)
WSB/EiJ MGP_WSBEiJ_G0018206
 protein coding gene Chr11:84078127-84090011 (+)



Homology
more
  • Human Ortholog
    RASL10B, RAS like family 10 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASL10B, RAS like family 10 member B
  • Synonyms
    RRP17, VTS58635
  • Links
    NCBI Gene ID: 91608
    UniProt: Q96S79

  • Chr Location
    17q12; chr17:35731639-35743521 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele have smaller than normal large dense-core vesicles in atrial myocytes and exhibit impaired atrial natriuretic peptide secretion.
Gene Ontology
(GO)
Classifications
less
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    31
  • cDNA Data
    16
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 276952 NCBI Gene Model | MGI Sequence Detail 11903 C57BL/6J ±  kb
transcript NM_001013386 RefSeq | MGI Sequence Detail 3482 C57BL/6  
polypeptide Q5SSG5 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory