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Zfp469 Gene Detail
Summary
  • Symbol
    Zfp469
  • Name
    zinc finger protein 469
  • Synonyms
    Gm22, LOC195209
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684868
    NCBI Gene: 195209
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr8:122985359-122999389 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 70.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    200 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684868
protein coding gene Chr8:122770009-122999389 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007399
lincRNA gene Chr8:125800663-125803758 (+)
A/J MGP_AJ_G0007395
lincRNA gene Chr8:120590044-120593139 (+)
AKR/J MGP_AKRJ_G0007367
lincRNA gene Chr8:124111845-124114940 (+)
BALB/cJ MGP_BALBcJ_G0007373
lincRNA gene Chr8:120791692-120794787 (+)
C3H/HeJ MGP_C3HHeJ_G0007317
lincRNA gene Chr8:124810339-124813434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007544
lincRNA gene Chr8:129984423-129987504 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006737
lincRNA gene Chr8:113419022-113422121 (+)
CAST/EiJ MGP_CASTEiJ_G0007220
lincRNA gene Chr8:124878932-124882027 (+)
CBA/J MGP_CBAJ_G0007299
lincRNA gene Chr8:134790661-134793742 (+)
DBA/2J MGP_DBA2J_G0007322
lincRNA gene Chr8:119785402-119788483 (+)
FVB/NJ MGP_FVBNJ_G0007343
lincRNA gene Chr8:118903705-118907461 (+)
LP/J MGP_LPJ_G0007404
lincRNA gene Chr8:125926229-125929324 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007320
lincRNA gene Chr8:136965309-136968404 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007547
lincRNA gene Chr8:124291826-124294907 (+)
PWK/PhJ MGP_PWKPhJ_G0007161
lincRNA gene Chr8:119600037-119603217 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007068
lincRNA gene Chr8:123016065-123019159 (+)
WSB/EiJ MGP_WSBEiJ_G0007280
lincRNA gene Chr8:125043839-125046934 (+)



Homology
more
  • Human Ortholog
    ZNF469, zinc finger protein 469
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF469, zinc finger protein 469
  • Synonyms
    BCS, BCS1, Zfp469
  • Links
    NCBI Gene ID: 84627
    UniProt: Q96JG9

  • Chr Location
    16q24.2; chr16:88424805-88440757 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Zfp469 mouse models; 1 with human ZNF469 associations

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000043903 Ensembl Gene Model | MGI Sequence Detail 14031 C57BL/6J ±  kb
    transcript ENSMUST00000187142 Ensembl | MGI Sequence Detail 12777 Not Applicable  
    polypeptide ENSMUSP00000158621 Ensembl | MGI Sequence Detail 3765 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR036236 Zinc finger C2H2 superfamily
      IPR013087 Zinc finger C2H2-type
      IPR039270 Zinc finger protein 469
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 7
      Primer pair 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 21
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 2
      Phenotypes 4
    • Earliest
      J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
    • Latest
      J:311083 Stanton CM, et al., A mouse model of brittle cornea syndrome caused by mutation in Zfp469. Dis Model Mech. 2021 Sep 1;14(9):dmm049175

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    01/24/2023
    MGI 6.22
    The Jackson Laboratory