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Mir133a-1 Gene Detail
Summary
  • Symbol
    Mir133a-1
  • Name
    microRNA 133a-1
  • Synonyms
    mir-133a-1, Mirn133, Mirn133a-1, mmu-mir-133a-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676818
    NCBI Gene: 387151
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:10782909-10782976 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 5.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676818
miRNA gene Chr18:10782909-10782976 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008367
miRNA gene Chr18:7725479-7725546 (-)
A/J MGP_AJ_G0008356
miRNA gene Chr18:7673372-7673439 (-)
AKR/J MGP_AKRJ_G0008340
miRNA gene Chr18:7875197-7875264 (-)
BALB/cJ MGP_BALBcJ_G0008340
miRNA gene Chr18:7657802-7657869 (-)
C3H/HeJ MGP_C3HHeJ_G0008285
miRNA gene Chr18:7768311-7768378 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008539
miRNA gene Chr18:8179854-8179921 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007580
miRNA gene Chr18:7350417-7350484 (-)
CAST/EiJ MGP_CASTEiJ_G0008149
miRNA gene Chr18:7664357-7664424 (-)
CBA/J MGP_CBAJ_G0008252
miRNA gene Chr18:8240849-8240916 (-)
DBA/2J MGP_DBA2J_G0008283
miRNA gene Chr18:7541215-7541282 (-)
FVB/NJ MGP_FVBNJ_G0008307
miRNA gene Chr18:7488878-7488945 (-)
LP/J MGP_LPJ_G0008369
miRNA gene Chr18:7852668-7852735 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008271
miRNA gene Chr18:8485465-8485532 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008528
miRNA gene Chr18:7704945-7705012 (-)
PWK/PhJ MGP_PWKPhJ_G0008069
miRNA gene Chr18:7574195-7574262 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0008230
miRNA gene Chr18:7681174-7681241 (-)



Homology
more
  • Human Ortholog
    MIR133A1, microRNA 133a-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR133A1, microRNA 133a-1
  • Synonyms
    mir-133a-1, MIRN133A1
  • Links
    NCBI Gene ID: 406922

  • Chr Location
    chr18:21825698-21825785 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human MIR133A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    21 phenotypes from multigenic genotypes
    13 phenotype references
Mice homozygous for a knock-out allele are viable with no apparent defects in behavior, weight, or life span.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387151 NCBI Gene Model | MGI Sequence Detail 68 C57BL/6J ±  kb
transcript NR_029547 RefSeq | MGI Sequence Detail 68 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 6
    Primer pair 4
    Other 2
Other Database
Links
less
miRBase MI0000159
References
more
  • Summaries
    All 62
    Developmental Gene Expression 23
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:328212 Klockner I, et al., Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. Nat Commun. 2022 Jun 8;13(1):3180

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory