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Zfp189 Gene Detail
Summary
  • Symbol
    Zfp189
  • Name
    zinc finger protein 189
  • Synonyms
    C430015I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444707
    NCBI Gene: 230162
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:49521176-49531517 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 26.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444707
 protein coding gene Chr4:49521176-49531558 (+)
129S1/SvImJ ENSMUSG00200002330
 protein coding gene Chr4:45599313-45609648 (+)
A/J ENSMUSG00195005449
 protein coding gene Chr4:46016576-46026911 (+)
AKR/J ENSMUSG00220002598
 protein coding gene Chr4:45741161-45751503 (+)
BALB/cJ ENSMUSG00180029003
 protein coding gene Chr4:45603235-45613579 (+)
C3H/HeJ ENSMUSG00175020988
 protein coding gene Chr4:45752133-45762473 (+)
C57BL/6NJ ENSMUSG00215021565
 protein coding gene Chr4:45550197-45560538 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026012
 protein coding gene Chr4:43428901-43441023 (+)
CAST/EiJ ENSTCUG00005033903
 protein coding gene Chr4:45867288-45877611 (+)
CBA/J ENSMUSG00210019450
 protein coding gene Chr4:45457099-45467421 (+)
DBA/2J ENSMUSG00185031557
 protein coding gene Chr4:45815569-45825907 (+)
FVB/NJ ENSMUSG00205015576
 protein coding gene Chr4:45108037-45118376 (+)
JF1/MsJ ENSUMUG00000024398
 protein coding gene Chr4:46107256-46117599 (+)
LP/J ENSMUSG00230037826
 protein coding gene Chr4:49395054-49405387 (+)
NOD/ShiLtJ ENSMUSG00190024978
 protein coding gene Chr4:45706173-45716489 (+)
NZO/HlLtJ ENSMUSG00225002635
 protein coding gene Chr4:53985266-53995606 (+)
PWK/PhJ ENSLUMG00010012107
 protein coding gene Chr4:45020332-45030635 (+)
SPRET/EiJ ENSMSPG00010008321
 protein coding gene Chr4:46071584-46082377 (+)
WSB/EiJ ENSIUOG00005004350
 protein coding gene Chr4:45437675-45447984 (+)



Homology
more
  • Human Ortholog
    ZNF189, zinc finger protein 189
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF189, zinc finger protein 189
  • Links
    NCBI Gene ID: 7743
    UniProt: O75820

  • Chr Location
    9q31.1; chr9:101398851-101410660 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    674
  • Tissues
    54
  • cDNA Data
    16
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039634 Ensembl Gene Model | MGI Sequence Detail 10342 C57BL/6J ±  kb
transcript ENSMUST00000107696 Ensembl | MGI Sequence Detail 2965 Not Applicable  
polypeptide ENSMUSP00000103324 Ensembl | MGI Sequence Detail 608 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001909 Krueppel-associated box
    IPR036051 Krueppel-associated box domain superfamily
    IPR050826 Krueppel C2H2-type Zinc Finger
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:2140639
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory