About   Help   FAQ
Clptm1l Gene Detail
Summary
  • Symbol
    Clptm1l
  • Name
    CLPTM1-like
  • Synonyms
    C130052I12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442892
    NCBI Gene: 218335
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:73752125-73768724 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    485 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442892
 protein coding gene Chr13:73752121-73768758 (+)
129S1/SvImJ ENSMUSG00200010216
 protein coding gene Chr13:68143384-68159983 (+)
A/J ENSMUSG00195026757
 protein coding gene Chr13:68731388-68747987 (+)
AKR/J ENSMUSG00220033065
 protein coding gene Chr13:67325733-67342332 (+)
BALB/cJ ENSMUSG00180020546
 protein coding gene Chr13:69229761-69246360 (+)
C3H/HeJ ENSMUSG00175007501
 protein coding gene Chr13:69511274-69527873 (+)
C57BL/6NJ ENSMUSG00215007206
 protein coding gene Chr13:69295750-69312349 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018704
 protein coding gene Chr13:68243794-68260618 (+)
CAST/EiJ ENSTCUG00005011729
 protein coding gene Chr13:68817916-68834541 (+)
CBA/J ENSMUSG00210008584
 protein coding gene Chr13:68831078-68847677 (+)
DBA/2J ENSMUSG00185017742
 protein coding gene Chr13:72522624-72539223 (+)
FVB/NJ ENSMUSG00205021622
 protein coding gene Chr13:68209998-68226596 (+)
JF1/MsJ ENSUMUG00000021797
 protein coding gene Chr13:72288634-72305259 (+)
LP/J ENSMUSG00230023419
 protein coding gene Chr13:82444704-82461316 (+)
NOD/ShiLtJ ENSMUSG00190027389
 protein coding gene Chr13:68831327-68847925 (+)
NZO/HlLtJ ENSMUSG00225027784
 protein coding gene Chr13:74948593-74965192 (+)
PWK/PhJ ENSLUMG00010011182
 protein coding gene Chr13:68323588-68340222 (+)
SPRET/EiJ ENSMSPG00010029594
 protein coding gene Chr13:69209436-69226068 (+)
WSB/EiJ ENSIUOG00005019341
 protein coding gene Chr13:68087460-68104056 (+)



Homology
more
  • Human Ortholog
    CLPTM1L, CLPTM1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLPTM1L, CLPTM1 like
  • Synonyms
    CRR9
  • Links
    NCBI Gene ID: 81037
    UniProt: Q96KA5

  • Chr Location
    5p15.33; chr5:1317744-1345099 (-)  GRCh38
Human Diseases
more
  • Diseases
    11 with human CLPTM1L associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit partial prenatal and neonatal lethality; however, surviving mice are fertile and overtly normal with no significant alterations in the development, maturation and differentiation of B-lymphocytes or production of antibodies by antibody secreting cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    3
  • cDNA Data
    103
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021610 Ensembl Gene Model | MGI Sequence Detail 16600 C57BL/6J ±  kb
    transcript ENSMUST00000022102 Ensembl | MGI Sequence Detail 2340 Not Applicable  
    polypeptide ENSMUSP00000022102 Ensembl | MGI Sequence Detail 539 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      cDNA 103
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory