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Zscan5b Gene Detail
Summary
  • Symbol
    Zscan5b
  • Name
    zinc finger and SCAN domain containing 5B
  • Synonyms
    Zfg1, Zfp371
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159640
    NCBI Gene: 170734
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:6225277-6242416 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 3.61 cM, cytoband A1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    665 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2159640
protein coding gene Chr7:6225277-6242422 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031597
protein coding gene Chr7:3288520-3308280 (+)
A/J MGP_AJ_G0031571
protein coding gene Chr7:3200510-3222220 (+)
AKR/J MGP_AKRJ_G0031500
protein coding gene Chr7:3416462-3441872 (+)
BALB/cJ MGP_BALBcJ_G0031579
protein coding gene Chr7:3302380-3329306 (+)
C3H/HeJ MGP_C3HHeJ_G0031300
protein coding gene Chr7:3273507-3291263 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032041
protein coding gene Chr7:3487626-3506151 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029156
protein coding gene Chr7:2901570-2916455 (+)
CAST/EiJ MGP_CASTEiJ_G0030663
protein coding gene Chr7:3167537-3189283 (+)
CBA/J MGP_CBAJ_G0031257
protein coding gene Chr7:3583739-3604506 (+)
DBA/2J MGP_DBA2J_G0031416
protein coding gene Chr7:3229500-3246823 (+)
FVB/NJ MGP_FVBNJ_G0031369
protein coding gene Chr7:3226677-3245103 (+)
LP/J MGP_LPJ_G0031501
protein coding gene Chr7:3394199-3413223 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031408
protein coding gene Chr7:3591804-3611906 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032070
protein coding gene Chr7:3219691-3236823 (+)
PWK/PhJ MGP_PWKPhJ_G0030391
protein coding gene Chr7:3392029-3409946 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030217
protein coding gene Chr7:2803269-2821470 (+)
WSB/EiJ MGP_WSBEiJ_G0030758
protein coding gene Chr7:3370560-3388988 (+)



Homology
more
  • Human Ortholog
    ZSCAN5A, zinc finger and SCAN domain containing 5A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZSCAN5A, zinc finger and SCAN domain containing 5A
  • Synonyms
    ZNF495, ZSCAN5
  • Links
    NCBI Gene ID: 79149
    neXtProt AC: NX_Q9BUG6
    UniProt: Q9BUG6

  • Chr Location
    19q13.43; chr19:56219670-56368383 (-)  GRCh38

  • Human Ortholog
    ZSCAN5B, zinc finger and SCAN domain containing 5B
  • Synonyms
    ZNF371, ZNF495B
  • Links
    NCBI Gene ID: 342933
    neXtProt AC: NX_A6NJL1
    UniProt: A6NJL1

  • Chr Location
    19q13.43; chr19:56189686-56197890 (-)  GRCh38

  • Human Ortholog
    ZSCAN5C, zinc finger and SCAN domain containing 5C
  • Synonyms
    ZNF495C, ZSCAN5CP
  • Links
    NCBI Gene ID: 649137
    UniProt: A6NGD5

  • Chr Location
    chr19:56202273-56209461 (+)  GRCh38

  • Human Ortholog
    ZSCAN5DP, zinc finger and SCAN domain containing 5D pseudogene
  • Synonyms
    ZNF495D, ZSCAN5D
  • Links
    NCBI Gene ID: 646698
    UniProt: P0CG00

  • Chr Location
    19q13.43; chr19:56243925-56247482 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased chromosomal stability.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 170734 NCBI Gene Model | MGI Sequence Detail 17140 C57BL/6J ±  kb
    transcript NM_133204 RefSeq | MGI Sequence Detail 1969 C57BL/6  
    polypeptide NP_573467 RefSeq | MGI Sequence Detail 468 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 18
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 6
      Gene Ontology 2
      Phenotypes 4
    • Earliest
      J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    07/05/2024
    MGI 6.24
    The Jackson Laboratory