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Copz2 Gene Detail
Summary
  • Symbol
    Copz2
  • Name
    coatomer protein complex, subunit zeta 2
  • Synonyms
    1110012D12Rik, nonclathrin coat protein zeta2-COP, zeta2-COP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929008
    NCBI Gene: 56358
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96740702-96752029 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 60.13 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    466 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929008
protein coding gene Chr11:96740696-96752029 (+)
129S1/SvImJ ENSMUSG00200048072
protein coding gene Chr11:93985237-93996644 (+)
A/J ENSMUSG00195050561
protein coding gene Chr11:93704787-93716353 (+)
AKR/J ENSMUSG00220044348
protein coding gene Chr11:93963931-93975504 (+)
BALB/cJ ENSMUSG00180051963
protein coding gene Chr11:93969872-93981277 (+)
C3H/HeJ ENSMUSG00175050825
protein coding gene Chr11:93965666-93976974 (+)
C57BL/6NJ ENSMUSG00215053682
protein coding gene Chr11:93558323-93569719 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017038
protein coding gene Chr11:92619358-92631297 (+)
CAST/EiJ ENSTCUG00005046802
protein coding gene Chr11:93408900-93426743 (+)
CBA/J ENSMUSG00210052604
protein coding gene Chr11:93667036-93678610 (+)
DBA/2J ENSMUSG00185041102
protein coding gene Chr11:94015523-94026904 (+)
FVB/NJ ENSMUSG00205025736
protein coding gene Chr11:93872220-93883612 (+)
JF1/MsJ ENSUMUG00000022003
protein coding gene Chr11:94320108-94331688 (+)
LP/J ENSMUSG00230050224
protein coding gene Chr11:95068231-95079642 (+)
NOD/ShiLtJ ENSMUSG00190051111
protein coding gene Chr11:94063427-94074836 (+)
NZO/HlLtJ ENSMUSG00225050719
protein coding gene Chr11:97123758-97135137 (+)
PWK/PhJ ENSLUMG00010050851
protein coding gene Chr11:93871855-93883392 (+)
SPRET/EiJ ENSMSPG00010043287
protein coding gene Chr11:94368746-94380563 (+)
WSB/EiJ ENSIUOG00005045130
protein coding gene Chr11:93817882-93829285 (+)



Homology
more
  • Human Ortholog
    COPZ2, coat protein complex I subunit zeta 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COPZ2, coat protein complex I subunit zeta 2
  • Synonyms
    zeta2-COP
  • Links
    NCBI Gene ID: 51226
    UniProt: Q9P299

  • Chr Location
    17q21.32; chr17:48026142-48048053 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56358 NCBI Gene Model | MGI Sequence Detail 11328 C57BL/6J ±  kb
transcript NM_019877 RefSeq | MGI Sequence Detail 937 Not Specified  
polypeptide Q9JHH9 UniProt | EBI | MGI Sequence Detail 205 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915758
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory