Tmem44 MGI Mouse Gene Detail - MGI:1924489

Symbol

Tmem44
Name

transmembrane protein 44
Synonyms

1700007N03Rik, 9330161C17Rik

Feature Type

protein coding gene
IDs

MGI:1924489
NCBI Gene: 224090
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr16:30330673-30369643 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 21.34 cM
Mapping Data

2 experiments

SNPs within 2kb

1758 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924489	protein coding gene	Chr16:30330673-30369660 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022713	protein coding gene	Chr16:28419635-28459377 (-)
A/J	MGP_AJ_G0022676	protein coding gene	Chr16:27112529-27152737 (-)
AKR/J	MGP_AKRJ_G0022650	protein coding gene	Chr16:28141460-28181956 (-)
BALB/cJ	MGP_BALBcJ_G0022680	protein coding gene	Chr16:27285102-27325895 (-)
C3H/HeJ	MGP_C3HHeJ_G0022445	protein coding gene	Chr16:28243125-28284631 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023129	protein coding gene	Chr16:29037555-29079010 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020647	protein coding gene	Chr16:27545742-27585198 (-)
CAST/EiJ	MGP_CASTEiJ_G0021973	protein coding gene	Chr16:28339352-28382292 (-)
CBA/J	MGP_CBAJ_G0022415	protein coding gene	Chr16:30263226-30307320 (-)
DBA/2J	MGP_DBA2J_G0022548	protein coding gene	Chr16:26987269-27027169 (-)
FVB/NJ	MGP_FVBNJ_G0022523	protein coding gene	Chr16:26966633-27006767 (-)
LP/J	MGP_LPJ_G0022615	protein coding gene	Chr16:28236131-28281039 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022542	protein coding gene	Chr16:29764199-29805361 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023141	protein coding gene	Chr16:28100173-28139988 (-)
PWK/PhJ	MGP_PWKPhJ_G0021712	protein coding gene	Chr16:27298970-27338455 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021543	protein coding gene	Chr16:27855448-27900473 (-)
WSB/EiJ	MGP_WSBEiJ_G0022017	protein coding gene	Chr16:28042225-28084997 (-)

Human Ortholog

TMEM44, transmembrane protein 44

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM44, transmembrane protein 44
Links

HGNC:25120

NCBI Gene ID: 93109

UniProt: Q2T9K0
Chr Location

3q29; chr3:194587673-194633689 (-) GRCh38

MGI Vertebrate Homology

Tmem44 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TMEM44
Gene Tree

Tmem44

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

8
Endonuclease-mediated

3
Gene trapped

2
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

22 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

776
Tissues

10
cDNA Data

51
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tmem44

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All Sequences

92
RefSeq

34
UniProt

9
CCDS

CCDS37310.1

Ensembl

ENSMUSG00000022537 (Evidence)
NCBI Gene

224090

			Length	Strain/Species	Flank
genomic	224090	NCBI Gene Model \| MGI Sequence Detail	38971	C57BL/6J	± kb
transcript	NM_001361297	RefSeq \| MGI Sequence Detail	5250	C57BL/6
polypeptide	NP_001344343	RefSeq \| MGI Sequence Detail	460	C57BL/6

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UniProt

9 Sequences
InterPro Domains

IPR051415 Lysosomal/Vacuolar Amino Acid Transporter 1

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All nucleic 51

cDNA 51

Microarray probesets 5

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MGI:1922707

Summaries

All 28

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Tmem44:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr140719	Chr16:30369378-30369412 (-)	248 bp
Tssr140718	Chr16:30369347-30369367 (-)	286 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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