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Elp6 Gene Detail
Summary
  • Symbol
    Elp6
  • Name
    elongator acetyltransferase complex subunit 6
  • Synonyms
    2610001P13Rik, 2610002I17Rik, Tmem103
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919349
    NCBI Gene: 72341
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110134241-110151170 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919349
protein coding gene Chr9:110133321-110151170 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035344
protein coding gene Chr9:112447039-112465704 (+)
A/J MGP_AJ_G0035325
protein coding gene Chr9:108360392-108379442 (+)
AKR/J MGP_AKRJ_G0035256
protein coding gene Chr9:111052411-111068863 (+)
BALB/cJ MGP_BALBcJ_G0035320
protein coding gene Chr9:108103661-108122290 (+)
C3H/HeJ MGP_C3HHeJ_G0035028
protein coding gene Chr9:111556849-111575461 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035842
protein coding gene Chr9:115500273-115518323 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032728
protein coding gene Chr9:105590149-105604245 (+)
CAST/EiJ MGP_CASTEiJ_G0034334
protein coding gene Chr9:111345201-111361019 (+)
CBA/J MGP_CBAJ_G0034995
protein coding gene Chr9:119799118-119816491 (+)
DBA/2J MGP_DBA2J_G0035154
protein coding gene Chr9:107824236-107841128 (+)
FVB/NJ MGP_FVBNJ_G0035101
protein coding gene Chr9:106646594-106664287 (+)
LP/J MGP_LPJ_G0035233
protein coding gene Chr9:112741681-112759000 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035141
protein coding gene Chr9:121158041-121178139 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035862
protein coding gene Chr9:111375338-111397210 (+)
PWK/PhJ MGP_PWKPhJ_G0034041
protein coding gene Chr9:108064113-108079969 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033876
protein coding gene Chr9:111470196-111486655 (+)
WSB/EiJ MGP_WSBEiJ_G0034455
protein coding gene Chr9:111258949-111277463 (+)



Homology
more
  • Human Ortholog
    ELP6, elongator acetyltransferase complex subunit 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELP6, elongator acetyltransferase complex subunit 6
  • Synonyms
    C3orf75, TMEM103
  • Links
    NCBI Gene ID: 54859
    neXtProt AC: NX_Q0PNE2
    UniProt: Q0PNE2

  • Chr Location
    3p21.31; chr3:47495640-47513712 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced single point mutation exhibit impaired coordination.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000054836 Ensembl Gene Model | MGI Sequence Detail 16930 C57BL/6J ±  kb
    transcript ENSMUST00000199592 Ensembl | MGI Sequence Detail 1304 Not Applicable  
    polypeptide ENSMUSP00000142823 Ensembl | MGI Sequence Detail 266 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 24

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1919591, MGI:2143264
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:280869 Freeman S, et al., Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Rep. 2019 Sep;20(9):e47097

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory