Elp6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elp6
elongator acetyltransferase complex subunit 6
MGI:1919349

21 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elp6^em1(IMPC)J/Elp6⁺ C57BL/6NJ-Elp6^em1(IMPC)J/Mmjax	decreased grip strength	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
Elp6^em1(IMPC)J/Elp6^em1(IMPC)J C57BL/6NJ-Elp6^em1(IMPC)J/Mmjax	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Elp6^em1Bjw/Elp6⁺ Not Specified	abnormal excitatory postsynaptic potential	J:360936
	abnormal hippocampal pyramidal neuron dendrite morphology	J:360936
	ataxia	J:360936
	growth/size/body region phenotype	J:360936
	impaired balance	J:360936
	impaired limb coordination	J:360936
	increased locomotor activity	J:360936
	limb grasping	J:360936
	muscle weakness	J:360936
	nervous system phenotype	J:360936
	premature death	J:360936
	slow postnatal weight gain	J:360936
	tremors	J:360936
Elp6^em1Bjw/Elp6^em1Bjw C57BL/6-Elp6^em1Bjw	abnormal excitatory postsynaptic potential	J:360936
	abnormal hippocampal pyramidal neuron dendrite morphology	J:360936
	ataxia	J:360936
	normal growth/size/body region phenotype	J:360936
	impaired balance	J:360936
	impaired limb coordination	J:360936
	increased locomotor activity	J:360936
	limb grasping	J:360936
	muscle weakness	J:360936
	normal nervous system phenotype	J:360936
	premature death	J:360936
	slow postnatal weight gain	J:360936
	tremors	J:360936
Elp6^m1Anu/Elp6^m1Anu C57BL/6JSfdAnu-Elp6^m1Anu	impaired coordination	J:104190

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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