Triap1 MGI Mouse Gene Detail - MGI:1916326 - TP53 regulated inhibitor of apoptosis 1

Symbol

Triap1
Name

TP53 regulated inhibitor of apoptosis 1
Synonyms

1810015M01Rik

Feature Type

protein coding gene
IDs

MGI:1916326
NCBI Gene: 69076
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr5:115479290-115481612 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 56.06 cM
Mapping Data

2 experiments

SNPs within 2kb

143 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916326	protein coding gene	Chr5:115479284-115481628 (+)
129S1/SvImJ	ENSMUSG00200021715	protein coding gene	Chr5:109218740-109221083 (+)
A/J	ENSMUSG00195039271	protein coding gene	Chr5:108733125-108735463 (+)
AKR/J	ENSMUSG00220049682	protein coding gene	Chr5:108248131-108250473 (+)
BALB/cJ	ENSMUSG00180045835	protein coding gene	Chr5:108869443-108871785 (+)
C3H/HeJ	ENSMUSG00175044219	protein coding gene	Chr5:110856828-110859167 (+)
C57BL/6NJ	ENSMUSG00215011750	protein coding gene	Chr5:108880206-108882550 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027624	protein coding gene	Chr5:108282046-108284792 (+)
CAST/EiJ	ENSTCUG00005022140	protein coding gene	Chr5:108057770-108060101 (+)
CBA/J	ENSMUSG00210031104	protein coding gene	Chr5:109608224-109610563 (+)
DBA/2J	ENSMUSG00185053412	protein coding gene	Chr5:112667513-112669855 (+)
FVB/NJ	ENSMUSG00205049314	protein coding gene	Chr5:108507202-108509541 (+)
JF1/MsJ	ENSUMUG00000037785	protein coding gene	Chr5:115487609-115489938 (+)
LP/J	ENSMUSG00230048112	protein coding gene	Chr5:116756931-116759273 (+)
NOD/ShiLtJ	ENSMUSG00190023467	protein coding gene	Chr5:108546262-108548598 (+)
NZO/HlLtJ	ENSMUSG00225015192	protein coding gene	Chr5:124416942-124419284 (+)
PWK/PhJ	ENSLUMG00010026092	protein coding gene	Chr5:107390325-107392655 (+)
SPRET/EiJ	ENSMSPG00010045458	protein coding gene	Chr5:110671703-110674224 (+)
WSB/EiJ	ENSIUOG00005037328	protein coding gene	Chr5:111249418-111251759 (+)

Human Ortholog

TRIAP1, TP53 regulated inhibitor of apoptosis 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TRIAP1, TP53 regulated inhibitor of apoptosis 1
Synonyms

HSPC132, MDM35, P53CSV, WF-1
Links

HGNC:26937

NCBI Gene ID: 51499

UniProt: O43715
Chr Location

12q24.31; chr12:120443958-120446412 (-) GRCh38

MGI Vertebrate Homology

Triap1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TRIAP1
Gene Tree

Triap1

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Phenotype Summary

13 phenotype references

All Mutations and Alleles

14
Chemically induced (other)

1
Endonuclease-mediated

4
Gene trapped

6
Radiation induced

1
Targeted

2
Genomic Mutations

2 involving Triap1
Find Mice (IMSR)

5 strains or lines available

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All GO Annotations

49
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

599
Tissues

1
cDNA Data

72
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase triap1

ZFIN triap1

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All Sequences

34
RefSeq

2
UniProt

1
CCDS

CCDS39228.1

Ensembl

ENSMUSG00000029535 (Evidence)
NCBI Gene

69076

			Length	Strain/Species	Flank
genomic	69076	NCBI Gene Model \| MGI Sequence Detail	2323	C57BL/6J	± kb
transcript	NM_026933	RefSeq \| MGI Sequence Detail	1066	C57BL/6
polypeptide	Q9D8Z2	UniProt \| EBI \| MGI Sequence Detail	76	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000016637 TP53-regulated inhibitor of apoptosis 1

(term hierarchy)
InterPro Domains

IPR007918 Mitochondrial distribution/morphology family 35/apoptosis

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All nucleic 73

cDNA 72

Primer pair 1

Microarray probesets 3

less

MGI:2141053, MGI:2141091

Summaries

All 40

Developmental Gene Expression 1

Gene Ontology 6

Phenotypes 13
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:344404 Ma J, et al., CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise. Cell Rep. 2023 Dec 28;43(1):113626

TSS for Triap1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr48222	Chr5:115479284-115479329 (+)	17 bp
Tssr48223	Chr5:115479347-115479356 (+)	62 bp
Tssr48224	Chr5:115479374-115479383 (+)	89 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24