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Ergic1 Gene Detail
Summary
  • Symbol
    Ergic1
  • Name
    endoplasmic reticulum-golgi intermediate compartment 1
  • Synonyms
    1200007D18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914708
    NCBI Gene: 67458
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26780463-26875908 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.34 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3126 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914708
protein coding gene Chr17:26779736-26875908 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023403
protein coding gene Chr17:25747479-25845753 (+)
A/J MGP_AJ_G0023362
protein coding gene Chr17:24954863-25050653 (+)
AKR/J MGP_AKRJ_G0023328
protein coding gene Chr17:25083488-25180502 (+)
BALB/cJ MGP_BALBcJ_G0023367
protein coding gene Chr17:25209472-25305432 (+)
C3H/HeJ MGP_C3HHeJ_G0023127
protein coding gene Chr17:25475959-25574258 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023807
protein coding gene Chr17:26800798-26897468 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021282
protein coding gene Chr17:22411156-22508442 (+)
CAST/EiJ MGP_CASTEiJ_G0022628
protein coding gene Chr17:25406291-25505084 (+)
CBA/J MGP_CBAJ_G0023102
protein coding gene Chr17:27781688-27881233 (+)
DBA/2J MGP_DBA2J_G0023232
protein coding gene Chr17:24544023-24640220 (+)
FVB/NJ MGP_FVBNJ_G0023202
protein coding gene Chr17:24322371-24418405 (+)
LP/J MGP_LPJ_G0023309
protein coding gene Chr17:26014960-26110827 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023221
protein coding gene Chr17:27306184-27404246 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023849
protein coding gene Chr17:25432791-25531498 (+)
PWK/PhJ MGP_PWKPhJ_G0022377
protein coding gene Chr17:23338956-23436632 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022195
protein coding gene Chr17:23496626-23606092 (+)
WSB/EiJ MGP_WSBEiJ_G0022691
protein coding gene Chr17:25485889-25583904 (+)



Homology
more
  • Human Ortholog
    ERGIC1, endoplasmic reticulum-golgi intermediate compartment 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERGIC1, endoplasmic reticulum-golgi intermediate compartment 1
  • Synonyms
    AMC2, AMCN, ERGIC32, ERGIC-32, NET24
  • Links
    NCBI Gene ID: 57222
    neXtProt AC: NX_Q969X5
    UniProt: Q969X5

  • Chr Location
    5q35.1; chr5:172834251-172952792 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human ERGIC1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001576 Ensembl Gene Model | MGI Sequence Detail 95446 C57BL/6J ±  kb
transcript ENSMUST00000167662 Ensembl | MGI Sequence Detail 2754 Not Applicable  
polypeptide ENSMUSP00000132922 Ensembl | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000007174 endoplasmic reticulum-Golgi intermediate compartment protein 1
  • InterPro Domains
    IPR045888 Endoplasmic reticulum vesicle transporter
    IPR012936 Endoplasmic reticulum vesicle transporter, C-terminal
    IPR039542 Endoplasmic reticulum vesicle transporter, N-terminal
  • GlyGen
    Q9DC16 1 site
Molecular
Reagents
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  • All nucleic 121
    cDNA 121

    Microarray probesets 6
References
more
  • Summaries
    All 42
    Gene Ontology 4
    Phenotypes 17
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory