Fam187a Gene Detail

Summary

• Symbol
  Fam187a
• Name
  family with sequence similarity 187, member A
• Synonyms
  4933439F11Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1914034
  NCBI Gene: 66784
• Alliance
  genome feature page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr11:102775995-102777557 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 66.48 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  150 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914034	protein coding gene	Chr11:102775995-102777557 (+)
129S1/SvImJ	ENSMUSG00200050066	protein coding gene	Chr11:100070666-100072230 (+)
A/J	ENSMUSG00195049381	protein coding gene	Chr11:99765957-99767521 (+)
AKR/J	ENSMUSG00220046756	protein coding gene	Chr11:99978347-99979909 (+)
BALB/cJ	ENSMUSG00180050420	protein coding gene	Chr11:100116724-100118286 (+)
C3H/HeJ	ENSMUSG00175049003	protein coding gene	Chr11:100044220-100045784 (+)
C57BL/6NJ	ENSMUSG00215051314	protein coding gene	Chr11:99598044-99599606 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017265	protein coding gene	Chr11:98852253-98853819 (+)
CAST/EiJ	ENSTCUG00005048933	protein coding gene	Chr11:99539511-99541075 (+)
CBA/J	ENSMUSG00210053036	protein coding gene	Chr11:99741779-99743343 (+)
DBA/2J	ENSMUSG00185046011	protein coding gene	Chr11:100094041-100095605 (+)
FVB/NJ	ENSMUSG00205045402	protein coding gene	Chr11:99928762-99930324 (+)
JF1/MsJ	ENSUMUG00000045074	protein coding gene	Chr11:100348430-100349991 (+)
LP/J	ENSMUSG00230031817	protein coding gene	Chr11:101146507-101148071 (+)
NOD/ShiLtJ	ENSMUSG00190041743	protein coding gene	Chr11:100125015-100126577 (+)
NZO/HlLtJ	ENSMUSG00225052260	protein coding gene	Chr11:103161415-103162977 (+)
PWK/PhJ	ENSLUMG00010048702	protein coding gene	Chr11:99877534-99879095 (+)
SPRET/EiJ	ENSMSPG00010047384	protein coding gene	Chr11:100382845-100384409 (+)
WSB/EiJ	ENSIUOG00005049133	protein coding gene	Chr11:99881539-99883101 (+)

Homology

• Human Ortholog
  FAM187A, family with sequence similarity 187 member A

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FAM187A, family with sequence similarity 187 member A
  
• Links
  HGNC:35153

  NCBI Gene ID: 100528020

  UniProt: A6NFU0

  
  
• Chr Location
  17q21.31; chr17:44903433-44905390 (+)  GRCh38

---

• MGI Vertebrate Homology
  Fam187a stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: FAM187A
• Gene Tree
  Fam187a
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  2
• Targeted
  1
• Genomic Mutations
  1 involving Fam187a
• Incidental Mutations
  CvDC
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  597
• cDNA Data
  6

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS48949.1

• Ensembl
  ENSMUSG00000075510 (Evidence)
• NCBI Gene
  66784

Representative Sequences			Length	Strain/Species
genomic	66784	NCBI Gene Model | MGI Sequence Detail	1563	C57BL/6J
transcript	NM_025766	RefSeq | MGI Sequence Detail	1563	C57BL/6
polypeptide	Q9D3R5	UniProt | EBI | MGI Sequence Detail	417	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000031731 Ig-like V-type domain-containing protein FAM187A
  (term hierarchy)
• InterPro Domains
  IPR039311 FAM187A/B
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
• GlyGen
  Q9D3R5 2 sites

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 1

References

• Summaries
  All 26

  Gene Ontology 1

  Phenotypes 8
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

TSS for Fam187a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105291	Chr11:102775966-102775979 (+)	-22 bp
Tssr105292	Chr11:102775986-102776000 (+)	-2 bp