About   Help   FAQ
Cdc34b Gene Detail
Summary
  • Symbol
    Cdc34b
  • Name
    cell division cycle 34B
  • Synonyms
    Cdc34-ps
Location &
Maps
more
  • Sequence Map
    Chr11:94632663-94633840 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 58.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858429
 protein coding gene Chr11:94632608-94633859 (+)
129S1/SvImJ ENSMUSG00200049117
 protein coding gene Chr11:91875860-91877093 (+)
A/J ENSMUSG00195008687
 protein coding gene Chr11:91614125-91615376 (+)
AKR/J ENSMUSG00220011904
 protein coding gene Chr11:91873047-91874298 (+)
BALB/cJ ENSMUSG00180011043
 protein coding gene Chr11:91844657-91845890 (+)
C3H/HeJ ENSMUSG00175051720
 protein coding gene Chr11:91873695-91874946 (+)
C57BL/6NJ ENSMUSG00215052209
 protein coding gene Chr11:91448876-91450127 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016992
 protein coding gene Chr11:90462948-90464195 (+)
CAST/EiJ ENSTCUG00005016688
 protein coding gene Chr11:91305164-91306402 (+)
CBA/J ENSMUSG00210038419
 protein coding gene Chr11:91577114-91578365 (+)
DBA/2J ENSMUSG00185051832
 protein coding gene Chr11:91897600-91898851 (+)
FVB/NJ ENSMUSG00205032138
 protein coding gene Chr11:91776659-91777909 (+)
JF1/MsJ ENSUMUG00000026414
 protein coding gene Chr11:92227608-92228859 (+)
LP/J ENSMUSG00230045948
 protein coding gene Chr11:92959113-92960346 (+)
NOD/ShiLtJ ENSMUSG00190051552
 protein coding gene Chr11:91938403-91939635 (+)
NZO/HlLtJ ENSMUSG00225049084
 protein coding gene Chr11:95005359-95006610 (+)
PWK/PhJ ENSLUMG00010027543
 protein coding gene Chr11:91776616-91777867 (+)
SPRET/EiJ ENSMSPG00010026615
 protein coding gene Chr11:92277151-92278408 (+)
WSB/EiJ ENSIUOG00005049402
 protein coding gene Chr11:91720986-91722219 (+)



Homology
more
  • Human Ortholog
    CDC34, cell division cycle 34, ubiquitin conjugating enzyme
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC34, cell division cycle 34, ubiquitin conjugating enzyme
  • Synonyms
    E2-CDC34, UBC3, UBCH3, UBE2R1
  • Links
    NCBI Gene ID: 997
    UniProt: P49427

  • Chr Location
    19p13.3; chr19:531721-542092 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
  • All Sequences
    28
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 111266 NCBI Gene Model | MGI Sequence Detail 1178 C57BL/6J ±  kb
polypeptide A0A140T8I4 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • EC
    2.3.2.23
  • InterPro Domains
    IPR023313 Ubiquitin-conjugating enzyme, active site
    IPR050113 Ubiquitin-conjugating enzyme E2-like
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
    IPR000608 Ubiquitin-conjugating (UBC), catalytic core domain
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 20
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:15595 Plon SE, et al., Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10484-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory