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Fbxo31 Gene Detail
Summary
  • Symbol
    Fbxo31
  • Name
    F-box protein 31
  • Synonyms
    1110003O08Rik, 2310046N15Rik, Fbx14, Fbxo14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354708
    NCBI Gene: 76454
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:122276179-122305545 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 70.65 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1124 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354708
 protein coding gene Chr8:122276179-122305607 (-)
129S1/SvImJ ENSMUSG00200041437
 protein coding gene Chr8:116612260-116641625 (-)
A/J ENSMUSG00195025096
 protein coding gene Chr8:116903837-116933203 (-)
AKR/J ENSMUSG00220038870
 protein coding gene Chr8:117094066-117123428 (-)
BALB/cJ ENSMUSG00180022802
 protein coding gene Chr8:116949586-116978947 (-)
C3H/HeJ ENSMUSG00175025735
 protein coding gene Chr8:117005865-117035231 (-)
C57BL/6NJ ENSMUSG00215021351
 protein coding gene Chr8:116580104-116609473 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031648
 protein coding gene Chr8:112708686-112739716 (-)
CAST/EiJ ENSTCUG00005030367
 protein coding gene Chr8:116340066-116369343 (-)
CBA/J ENSMUSG00210036209
 protein coding gene Chr8:116933499-116962870 (-)
DBA/2J ENSMUSG00185035179
 protein coding gene Chr8:123037560-123066927 (-)
FVB/NJ ENSMUSG00205033705
 protein coding gene Chr8:115906917-115936279 (-)
JF1/MsJ ENSUMUG00000010714
 protein coding gene Chr8:125342111-125371413 (-)
LP/J ENSMUSG00230029200
 protein coding gene Chr8:126665447-126694808 (-)
NOD/ShiLtJ ENSMUSG00190017820
 protein coding gene Chr8:117041289-117070652 (-)
NZO/HlLtJ ENSMUSG00225042136
 protein coding gene Chr8:130038023-130067390 (-)
PWK/PhJ ENSLUMG00010032003
 protein coding gene Chr8:116749659-116779044 (-)
SPRET/EiJ ENSMSPG00010032396
 protein coding gene Chr8:118950536-118977893 (-)
WSB/EiJ ENSIUOG00005029406
 protein coding gene Chr8:117742872-117772236 (-)



Homology
more
  • Human Ortholog
    FBXO31, F-box protein 31
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO31, F-box protein 31
  • Synonyms
    FBX14, Fbx31, FBXO14, MRT45, pp2386
  • Links
    NCBI Gene ID: 79791
    UniProt: Q5XUX0

  • Chr Location
    16q24.2; chr16:87326987-87392142 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human FBXO31 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    652
  • Tissues
    21
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052934 Ensembl Gene Model | MGI Sequence Detail 29367 C57BL/6J ±  kb
transcript ENSMUST00000059018 Ensembl | MGI Sequence Detail 4358 Not Applicable  
polypeptide ENSMUSP00000057573 Ensembl | MGI Sequence Detail 507 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1923541, MGI:1923704
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory