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Psg16 Gene Detail
Summary
  • Symbol
    Psg16
  • Name
    pregnancy specific beta-1-glycoprotein 16
  • Synonyms
    bCEA, Cea11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347249
    NCBI Gene: 26436
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16807965-16867375 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.15 cM, cytoband A2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2087 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347249
 protein coding gene Chr7:16807938-16867375 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031729
 protein coding gene Chr7:14853142-14889339 (+)
A/J MGP_AJ_G0031701
 protein coding gene Chr7:14557111-14583691 (+)
AKR/J MGP_AKRJ_G0031626
 protein coding gene Chr7:14901503-14939857 (+)
BALB/cJ MGP_BALBcJ_G0031708
 protein coding gene Chr7:14670811-14696346 (+)
C3H/HeJ MGP_C3HHeJ_G0031430
 protein coding gene Chr7:15097428-15122204 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032174
 protein coding gene Chr7:15584467-15607355 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029253
 protein coding gene Chr7:16105642-16132492 (+)
CAST/EiJ MGP_CASTEiJ_G0030781
 protein coding gene Chr7:11868380-11899089 (+)
CBA/J MGP_CBAJ_G0031389
 protein coding gene Chr7:16125372-16156718 (+)
DBA/2J MGP_DBA2J_G0031545
 protein coding gene Chr7:14453703-14477693 (+)
FVB/NJ MGP_FVBNJ_G0031501
 protein coding gene Chr7:14352980-14382419 (+)
LP/J MGP_LPJ_G0031630
 protein coding gene Chr7:15113295-15147434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031536
 protein coding gene Chr7:16028927-16057516 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032203
 protein coding gene Chr7:14703254-14729547 (+)
PWK/PhJ MGP_PWKPhJ_G0030505
 protein coding gene Chr7:11978691-12004012 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030332
 protein coding gene Chr7:9617850-9645713 (+)
WSB/EiJ MGP_WSBEiJ_G0030878
 protein coding gene Chr7:14760271-14788213 (+)



Homology
more
  • Human Ortholog
    CEACAM21, CEA cell adhesion molecule 21
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM21, CEA cell adhesion molecule 21
  • Synonyms
    CEACAM3, R29124_1
  • Links
    NCBI Gene ID: 90273
    UniProt: Q3KPI0

  • Chr Location
    19q13.2; chr19:41549518-41586844 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    10
  • cDNA Data
    116
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066760 Ensembl Gene Model | MGI Sequence Detail 59411 C57BL/6J ±  kb
transcript ENSMUST00000071399 Ensembl | MGI Sequence Detail 4421 Not Applicable  
polypeptide ENSMUSP00000071348 Ensembl | MGI Sequence Detail 395 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR050831 Carcinoembryonic antigen-related cell adhesion
    IPR013151 Immunoglobulin
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR003598 Immunoglobulin subtype 2
    IPR013106 Immunoglobulin V-set domain
  • GlyGen
    Q8K0U8 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 118
    cDNA 117
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-31056, MGI:104983
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:30292 Chen DS, et al., A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus. Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12095-9
  • Latest
    J:359865 Fan W, et al., SLC25A1 regulates placental development to ensure embryonic heart morphogenesis. Development. 2024 Nov 15;151(22):dev204290
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory