About   Help   FAQ
H2-M10.3 Gene Detail
Summary
  • Symbol
    H2-M10.3
  • Name
    histocompatibility 2, M region locus 10.3
  • Synonyms
    5.3H
Location &
Maps
more
  • Sequence Map
    Chr17:36675896-36679309 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1276524
 protein coding gene Chr17:36675895-36679309 (-)
129S1/SvImJ no annotation
A/J ENSMUSG00195033198
 protein coding gene Chr17:33354231-33357645 (-)
AKR/J ENSMUSG00220052011
 protein coding gene Chr17:32144823-32148228 (-)
BALB/cJ ENSMUSG00180028930
 protein coding gene Chr17:32817565-32820979 (-)
C3H/HeJ ENSMUSG00175028359
 protein coding gene Chr17:32030616-32034021 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005050235
 protein coding gene Chr17:33205398-33208812 (-)
CBA/J ENSMUSG00210051998
 protein coding gene Chr17:31852606-31856011 (-)
DBA/2J ENSMUSG00185051235
 protein coding gene Chr17:34798541-34801955 (-)
FVB/NJ ENSMUSG00205027231
 protein coding gene Chr17:32411001-32414415 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230054257
 protein coding gene Chr17:35943965-35947379 (-)
NOD/ShiLtJ ENSMUSG00190036361
 protein coding gene Chr17:32029468-32032882 (-)
NZO/HlLtJ ENSMUSG00225052774
 protein coding gene Chr17:37858398-37861812 (-)
PWK/PhJ ENSLUMG00010042506
 protein coding gene Chr17:31628638-31632056 (-)
SPRET/EiJ ENSMSPG00010035056
 protein coding gene Chr17:32916535-32918689 (-)
WSB/EiJ ENSIUOG00005046218
 protein coding gene Chr17:32930503-32933917 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 110696 NCBI Gene Model | MGI Sequence Detail 3414 C57BL/6J ±  kb
transcript NM_201608 RefSeq | MGI Sequence Detail 1592 ZRU/MplStud  
polypeptide NP_963902 RefSeq | MGI Sequence Detail 330 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050208 Antigen-presenting and immune regulatory MHC class I-related
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 4
    Genomic 4

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:45971 Arepalli SR, et al., Characterization of two class I genes from the H2-M region: evidence for a new subfamily. Immunogenetics. 1998;47(3):264-71
  • Latest
    J:207447 Leinders-Zufall T, et al., A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014 Apr 9;34(15):5121-33
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory