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Golgb1 Gene Detail
Summary
  • Symbol
    Golgb1
  • Name
    golgin B1
  • Synonyms
    6330407A06Rik, C130074L01Rik, F730017E11Rik, Giantin, Gm6840
  • Feature Type
    protein coding gene
  • IDs
    MGI:1099447
    NCBI Gene: 224139
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:36695502-36753447 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 26.19 cM, cytoband B4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1481 from dbSNP Build 142
  • Strain Annotations
    29
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1099447
 protein coding gene Chr16:36695455-36753447 (+)
129S1/SvImJ ENSMUSG00200029073
 protein coding gene Chr16:33642293-33645563 (+)
129S1/SvImJ ENSMUSG00200029246
 protein coding gene Chr16:33631306-33631803 (+)
A/J ENSMUSG00195010140
 protein coding gene Chr16:33188732-33192002 (+)
A/J ENSMUSG00195010164
 protein coding gene Chr16:33177745-33178242 (+)
AKR/J ENSMUSG00220028493
 protein coding gene Chr16:33555384-33555881 (+)
AKR/J ENSMUSG00220028107
 protein coding gene Chr16:33566367-33613661 (+)
BALB/cJ ENSMUSG00180012533
 protein coding gene Chr16:33393353-33393850 (+)
BALB/cJ ENSMUSG00180012496
 protein coding gene Chr16:33404342-33451636 (+)
C3H/HeJ ENSMUSG00175031322
 protein coding gene Chr16:33624711-33627981 (+)
C3H/HeJ ENSMUSG00175031474
 protein coding gene Chr16:33613722-33614219 (+)
C57BL/6NJ ENSMUSG00215018334
 protein coding gene Chr16:33466895-33467392 (+)
C57BL/6NJ ENSMUSG00215017928
 protein coding gene Chr16:33477886-33481156 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020722
 protein coding gene Chr16:33921270-33977994 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210026911
 protein coding gene Chr16:33670805-33671302 (+)
CBA/J ENSMUSG00210026814
 protein coding gene Chr16:33681795-33685065 (+)
DBA/2J ENSMUSG00185022652
 protein coding gene Chr16:33573835-33574332 (+)
DBA/2J ENSMUSG00185022575
 protein coding gene Chr16:33584822-33588092 (+)
FVB/NJ ENSMUSG00205021868
 protein coding gene Chr16:33530760-33531257 (+)
FVB/NJ ENSMUSG00205021059
 protein coding gene Chr16:33541750-33545021 (+)
JF1/MsJ ENSUMUG00000017211
 protein coding gene Chr16:33805691-33852961 (+)
LP/J ENSMUSG00230026225
 protein coding gene Chr16:36146034-36146531 (+)
LP/J ENSMUSG00230026141
 protein coding gene Chr16:36145604-36204315 (+)
NOD/ShiLtJ ENSMUSG00190022170
 protein coding gene Chr16:33703165-33706435 (+)
NOD/ShiLtJ ENSMUSG00190022332
 protein coding gene Chr16:33692185-33692682 (+)
NZO/HlLtJ ENSMUSG00225039441
 protein coding gene Chr16:39256386-39259656 (+)
NZO/HlLtJ ENSMUSG00225039472
 protein coding gene Chr16:39245399-39245896 (+)
PWK/PhJ ENSLUMG00010029126
 protein coding gene Chr16:33713142-33760766 (+)
SPRET/EiJ ENSMSPG00010016645
 protein coding gene Chr16:33684413-33732433 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    GOLGB1, golgin B1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GOLGB1, golgin B1
  • Synonyms
    GCP, GCP372, GOLIM1
  • Links
    NCBI Gene ID: 2804
    UniProt: Q14789

  • Chr Location
    3q13.33; chr3:121663199-121749966 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Golgb1 mouse models

Human Disease Mouse Models
      
IDs
 View 5 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    3 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout affects glycosylation of glycoproteins in the extra-cellular matrix of the palatal shelves, resulting in their failure to elevate and fuse, leading to cleft palate.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    21
  • cDNA Data
    133
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034243 Ensembl Gene Model | MGI Sequence Detail 57946 C57BL/6J ±  kb
    transcript ENSMUST00000039855 Ensembl | MGI Sequence Detail 10847 Not Applicable  
    polypeptide ENSMUSP00000045239 Ensembl | MGI Sequence Detail 3238 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      14 Sequences
    • InterPro Domains
      IPR026202 Golgin subfamily B member 1
    • GlyGen
      E9PVZ8 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 136
      Genomic 2
      cDNA 133
      Other 1
      Antibodies 5

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1925340, MGI:2146577, MGI:2443094, MGI:3779635
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 11
      Diseases 1
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:42083 Diella F, et al., Characterization of the INT6 mammary tumor gene product. DNA Cell Biol. 1997 Jul;16(7):839-47
    • Latest
      J:389866 Kim JA, et al., HAP1 interaction with KCNQ4 attenuates channel surface expression and function. Mol Cells. 2026 Mar;49(3):100322
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory