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Ifna11 Gene Detail
Summary
  • Symbol
    Ifna11
  • Name
    interferon alpha 11
  • Synonyms
    IFN-[a]11
Location &
Maps
more
  • Sequence Map
    Chr4:88738196-88738768 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109210
protein coding gene Chr4:88738156-88738802 (+)
129S1/SvImJ no annotation
A/J ENSMUSG00195009089
protein coding gene Chr4:84263373-84263945 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215014040
protein coding gene Chr4:84092283-84092855 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ ENSMUSG00205013328
protein coding gene Chr4:82607005-82607577 (+)
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ ENSMUSG00225002326
protein coding gene Chr4:92925031-92925603 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010014704
protein coding gene Chr4:84196784-84197356 (+)
WSB/EiJ ENSIUOG00005012106
protein coding gene Chr4:83561309-83561881 (+)



Homology
more
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Vertebrate Orthologs
    24
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Synonyms
    IFL, IFN, IFNA@, IFNA13, IFN-ALPHA, IFN-alphaD, leIF D
  • Links
    NCBI Gene ID: 3439
    UniProt: P0DY56

  • Chr Location
    9p21.3; chr9:21440439-21441316 (+)  GRCh38

  • Human Ortholog
    IFNA10, interferon alpha 10
  • Synonyms
    IFN-alphaC
  • Links
    NCBI Gene ID: 3446
    UniProt: P01566

  • Chr Location
    9p21.3; chr9:21206181-21207143 (-)  GRCh38

  • Human Ortholog
    IFNA13, interferon alpha 13
  • Links
    NCBI Gene ID: 3447
    UniProt: A0A087WWS6

  • Chr Location
    9p21.3; chr9:21367372-21368057 (-)  GRCh38

  • Human Ortholog
    IFNA14, interferon alpha 14
  • Synonyms
    IFN-alphaH, LEIF2H
  • Links
    NCBI Gene ID: 3448
    UniProt: P01570

  • Chr Location
    9p21.3; chr9:21239002-21240005 (-)  GRCh38

  • Human Ortholog
    IFNA16, interferon alpha 16
  • Synonyms
    IFN-alpha-16, IFN-alphaO
  • Links
    NCBI Gene ID: 3449
    UniProt: P05015

  • Chr Location
    9p21.3; chr9:21216373-21217311 (-)  GRCh38

  • Human Ortholog
    IFNA17, interferon alpha 17
  • Synonyms
    IFNA, IFN-alphaI, INFA, LEIF2C1
  • Links
    NCBI Gene ID: 3451
    UniProt: P01571

  • Chr Location
    9p21.3; chr9:21227243-21228222 (-)  GRCh38

  • Human Ortholog
    IFNA2, interferon alpha 2
  • Synonyms
    IFNA, IFNA2B, IFN-alpha-2, IFN-alphaA, leIF A
  • Links
    NCBI Gene ID: 3440
    UniProt: P01563

  • Chr Location
    9p21.3; chr9:21384255-21385398 (-)  GRCh38

  • Human Ortholog
    IFNA21, interferon alpha 21
  • Synonyms
    IFN-alphaI, leIF-F, LeIF F
  • Links
    NCBI Gene ID: 3452
    UniProt: P01568

  • Chr Location
    9p21.3; chr9:21165637-21166660 (-)  GRCh38

  • Human Ortholog
    IFNA4, interferon alpha 4
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187587 (-)  GRCh38

  • Human Ortholog
    IFNA5, interferon alpha 5
  • Synonyms
    IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF G
  • Links
    NCBI Gene ID: 3442
    UniProt: P01569

  • Chr Location
    9p21.3; chr9:21304326-21305313 (-)  GRCh38

  • Human Ortholog
    IFNA6, interferon alpha 6
  • Synonyms
    IFN-alphaK
  • Links
    NCBI Gene ID: 3443
    UniProt: P05013

  • Chr Location
    9p21.3; chr9:21350253-21350956 (-)  GRCh38

  • Human Ortholog
    IFNA7, interferon alpha 7
  • Synonyms
    IFNA-J, IFN-alphaJ
  • Links
    NCBI Gene ID: 3444
    UniProt: P01567

  • Chr Location
    9p21.3; chr9:21201469-21202205 (-)  GRCh38

  • Human Ortholog
    IFNA8, interferon alpha 8
  • Synonyms
    IFN-alphaB
  • Links
    NCBI Gene ID: 3445
    UniProt: P32881

  • Chr Location
    9p21.3; chr9:21409117-21410185 (+)  GRCh38

Human Diseases
more
  • Diseases
    6 with human IFNA1,IFNA17,IFNA2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000100549 Ensembl Gene Model | MGI Sequence Detail 573 C57BL/6J ±  kb
transcript ENSMUST00000170428 Ensembl | MGI Sequence Detail 573 Not Applicable  
polypeptide ENSMUSP00000127921 Ensembl | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 8
    cDNA 3
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38254
References
more
  • Summaries
    All 32
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:38311 Navarro S, et al., Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction. J Gen Virol. 1989 Jun;70(Pt 6):1381-9
  • Latest
    J:380758 Adams NM, et al., Chromatin-mediated anticipatory control of type I interferon production in plasmacytoid dendritic cells. Immunity. 2026 Feb 10;59(2):270-287.e11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory