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Rock1 Gene Detail
Summary
  • Symbol
    Rock1
  • Name
    Rho-associated coiled-coil containing protein kinase 1
  • Synonyms
    1110055K06Rik, Rock-I
  • Feature Type
    protein coding gene
  • IDs
    MGI:107927
    NCBI Gene: 19877
  • Alliance
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:10064401-10182045 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 4.91 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2145 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107927
protein coding gene Chr18:10064401-10182225 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024146
protein coding gene Chr18:6999567-7116477 (-)
A/J MGP_AJ_G0024108
protein coding gene Chr18:6951559-7072201 (-)
AKR/J MGP_AKRJ_G0024075
protein coding gene Chr18:7122330-7252354 (-)
BALB/cJ MGP_BALBcJ_G0024107
protein coding gene Chr18:6923527-7056277 (-)
C3H/HeJ MGP_C3HHeJ_G0023874
protein coding gene Chr18:7011879-7132088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024552
protein coding gene Chr18:7418899-7533199 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021991
protein coding gene Chr18:6636535-6757663 (-)
CAST/EiJ MGP_CASTEiJ_G0023351
protein coding gene Chr18:6928075-7048875 (-)
CBA/J MGP_CBAJ_G0023846
protein coding gene Chr18:7451426-7585248 (-)
DBA/2J MGP_DBA2J_G0023975
protein coding gene Chr18:6796028-6914958 (-)
FVB/NJ MGP_FVBNJ_G0023940
protein coding gene Chr18:6766037-6883414 (-)
LP/J MGP_LPJ_G0024058
protein coding gene Chr18:7106661-7241488 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023969
protein coding gene Chr18:7636933-7810210 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024598
protein coding gene Chr18:6947541-7070828 (-)
PWK/PhJ MGP_PWKPhJ_G0023097
protein coding gene Chr18:6834098-6961950 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022907
protein coding gene Chr18:7259392-7377993 (-)
WSB/EiJ MGP_WSBEiJ_G0023417
protein coding gene Chr18:6941195-7061755 (-)



Homology
more
  • Human Ortholog
    ROCK1, Rho associated coiled-coil containing protein kinase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ROCK1, Rho associated coiled-coil containing protein kinase 1
  • Synonyms
    P160ROCK, ROCK-I
  • Links
    NCBI Gene ID: 6093
    neXtProt AC: NX_Q13464
    UniProt: Q13464

  • Chr Location
    18q11.1; chr18:20944612-21111813 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    38 phenotypes from 7 alleles in 7 genetic backgrounds
    12 phenotypes from multigenic genotypes
    6 images
    65 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo