Rock1 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rock1
Rho-associated coiled-coil containing protein kinase 1
MGI:107927

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lepr^db/Lepr^db Rock1^tm1Leiw/Rock1^tm1Leiw involves: 129S7/SvEvBrd * C57BLKS/J * FVB/N	abnormal mitochondrial physiology	J:182287
	albuminuria	J:182287
	enlarged kidney	J:182287
	expanded mesangial matrix	J:182287
	hyperglycemia	J:182287
	increased body size	J:182287
	increased body weight	J:182287
	increased kidney weight	J:182287
	increased renal glomerulus apoptosis	J:182287
	increased renal glomerulus basement membrane thickness	J:182287
	oxidative stress	J:182287
	normal renal/urinary system phenotype	J:182287

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24