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Cel Gene Detail
Summary
  • Symbol
    Cel
  • Name
    carboxyl ester lipase
  • Synonyms
    1810036E18Rik, BAL
  • Feature Type
    protein coding gene
  • IDs
    MGI:88374
    NCBI Gene: 12613
  • Alliance
  • Transcription Start Sites
    36 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:28445831-28453415 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.38 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88374
protein coding gene Chr2:28445807-28453415 (-)
129S1/SvImJ ENSMUSG00200051882
protein coding gene Chr2:25415793-25423356 (-)
A/J ENSMUSG00195047011
protein coding gene Chr2:25508613-25516181 (-)
AKR/J ENSMUSG00220052977
protein coding gene Chr2:25626349-25633918 (-)
BALB/cJ ENSMUSG00180052165
protein coding gene Chr2:25527595-25535167 (-)
C3H/HeJ ENSMUSG00175053604
protein coding gene Chr2:25496845-25504412 (-)
C57BL/6NJ ENSMUSG00215048071
protein coding gene Chr2:25555624-25563187 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023353
protein coding gene Chr2:24421577-24429083 (-)
CAST/EiJ ENSTCUG00005052008
protein coding gene Chr2:25240701-25248297 (-)
CBA/J ENSMUSG00210015287
protein coding gene Chr2:25530438-25538002 (-)
DBA/2J ENSMUSG00185048378
protein coding gene Chr2:25422521-25430088 (-)
FVB/NJ ENSMUSG00205041580
protein coding gene Chr2:25274324-25281893 (-)
JF1/MsJ ENSUMUG00000054094
protein coding gene Chr2:25325206-25332788 (-)
LP/J ENSMUSG00230036110
protein coding gene Chr2:27351675-27359231 (-)
NOD/ShiLtJ ENSMUSG00190051942
protein coding gene Chr2:25529339-25536906 (-)
NZO/HlLtJ ENSMUSG00225006780
protein coding gene Chr2:35099440-35107007 (-)
PWK/PhJ ENSLUMG00010047584
protein coding gene Chr2:25403092-25410660 (-)
SPRET/EiJ ENSMSPG00010041530
protein coding gene Chr2:26132259-26139862 (-)
WSB/EiJ ENSIUOG00005051201
protein coding gene Chr2:25382452-25390023 (-)



Homology
more
  • Human Ortholog
    CEL, carboxyl ester lipase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEL, carboxyl ester lipase
  • Synonyms
    BAL, BSDL, BSSL, CEase, CELL, FAP, FAPP, MODY8
  • Links
    NCBI Gene ID: 1056
    UniProt: P19835

  • Chr Location
    9q34.13; chr9:133061981-133071861 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with Cel mouse models; 4 with human CEL associations

Human Disease Mouse Models
      
IDs
View 2 models
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 4 alleles in 5 genetic backgrounds
    9 phenotypes from multigenic genotypes
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced cholesteryl ester absorption.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12613 NCBI Gene Model | MGI Sequence Detail 7585 C57BL/6J ±  kb
    transcript NM_009885 RefSeq | MGI Sequence Detail 2080 ZRU/MplStud  
    polypeptide Q64285 UniProt | EBI | MGI Sequence Detail 599 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 301
      Genomic 4
      cDNA 294
      Primer pair 1
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-1918, MGI:1925734
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 10
      Phenotypes 18
    • Earliest
      J:4122 Wen PZ, et al., Chromosomal organization of the inducible and constitutive prostaglandin synthase/cyclooxygenase genes in mouse. Genomics. 1993 Feb;15(2):458-60
    • Latest
      J:337474 Cobo I, et al., NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory