Phenotypes Associated with This Genotype

Genotype
MGI:8255015

• Allelic Composition: Cel^{em2(CEL/CELP)Zlia}/Cel⁺
• Genetic Background: C57BL/6JSmoc-Cel^{em2(CEL/CELP)Zlia}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

pancreatic acinar cell atrophy ( J:338873 )

• acinar atrophy is seen in 14-month-old pancreas

endocrine/exocrine glands

abnormal pancreas morphology ( J:338873 )

• mice develop similar pancreatic lesions to homozygotes but with less severity and slower progression

• 14-month-old pancreas shows fatty changes

pancreatic acinar cell atrophy ( J:338873 )

• acinar atrophy is seen in 14-month-old pancreas

pancreas inflammation ( J:338873 )

• 14-month-old mice exhibit inflammatory infiltration in pancreas

immune system

pancreas inflammation ( J:338873 )

• 14-month-old mice exhibit inflammatory infiltration in pancreas

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
pancreatitis		DOID:4989	OMIM:167800	J:338873