About   Help   FAQ
Rbm24 Gene Detail
Summary
  • Symbol
    Rbm24
  • Name
    RNA binding motif protein 24
  • Synonyms
    6330546B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3610364
    NCBI Gene: 666794
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:46571910-46584571 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 23.61 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3610364
 protein coding gene Chr13:46571664-46584575 (+)
129S1/SvImJ ENSMUSG00200035440
 protein coding gene Chr13:43821635-43834283 (+)
A/J ENSMUSG00195027817
 protein coding gene Chr13:42882388-42895040 (+)
AKR/J ENSMUSG00220008583
 protein coding gene Chr13:42693160-42705868 (+)
BALB/cJ ENSMUSG00180008446
 protein coding gene Chr13:43188888-43201544 (+)
C3H/HeJ ENSMUSG00175027787
 protein coding gene Chr13:43153149-43165798 (+)
C57BL/6NJ ENSMUSG00215004864
 protein coding gene Chr13:43316449-43329111 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018481
 protein coding gene Chr13:41660059-41672603 (+)
CAST/EiJ ENSTCUG00005030122
 protein coding gene Chr13:43215557-43228084 (+)
CBA/J ENSMUSG00210026516
 protein coding gene Chr13:43158613-43171264 (+)
DBA/2J ENSMUSG00185029881
 protein coding gene Chr13:43978697-43991348 (+)
FVB/NJ ENSMUSG00205010084
 protein coding gene Chr13:42936205-42948859 (+)
JF1/MsJ ENSUMUG00000011700
 protein coding gene Chr13:43500220-43513007 (+)
LP/J ENSMUSG00230028660
 protein coding gene Chr13:53290829-53303484 (+)
NOD/ShiLtJ ENSMUSG00190012013
 protein coding gene Chr13:43377313-43389967 (+)
NZO/HlLtJ ENSMUSG00225036000
 protein coding gene Chr13:47060978-47073640 (+)
PWK/PhJ ENSLUMG00010020359
 protein coding gene Chr13:42343779-42356485 (+)
SPRET/EiJ ENSMSPG00010027494
 protein coding gene Chr13:42445790-42458531 (+)
WSB/EiJ ENSIUOG00005027183
 protein coding gene Chr13:42530963-42543649 (+)



Homology
more
  • Human Ortholog
    RBM24, RNA binding motif protein 24
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM24, RNA binding motif protein 24
  • Synonyms
    dJ259A10.1, RNPC6
  • Links
    NCBI Gene ID: 221662
    UniProt: Q9BX46

  • Chr Location
    6p22.3; chr6:17281361-17293871 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Rbm24 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit lethality between E12.5 and E13.5 with embryonic growth retardation, thin and unfused atrioventricular cushions, reduced myocardial trabeculation and increased apoptosis in the heart.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    66
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    84
  • cDNA Data
    34
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038132 Ensembl Gene Model | MGI Sequence Detail 12662 C57BL/6J ±  kb
    transcript ENSMUST00000037923 Ensembl | MGI Sequence Detail 3086 Not Applicable  
    polypeptide ENSMUSP00000043120 Ensembl | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 34
      Primer pair 3
      Other 3
      Antibodies 3

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1923426, MGI:2145271
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 11
      Diseases 1
      Gene Ontology 12
      Phenotypes 14
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:376781 Yang H, et al., Dysregulated RBM24 phosphorylation impairs APOE translation underlying psychological stress-induced cardiovascular disease. Nat Commun. 2024 Nov 23;15(1):10181
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory