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Ifi211 Gene Detail
Summary
  • Symbol
    Ifi211
  • Name
    interferon activated gene 211
  • Synonyms
    Ifi205b, Mnda
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041120
    NCBI Gene: 381308
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173723911-173740612 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 80.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041120
 protein coding gene Chr1:173723907-173740650 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215041946
 protein coding gene Chr1:170684486-170701187 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014925
 protein coding gene Chr1:164223594-164237151 (-)
CAST/EiJ ENSTCUG00005044172
 protein coding gene Chr1:169273449-169290151 (-)
CBA/J no annotation
DBA/2J ENSMUSG00185029026
 protein coding gene Chr1:175542660-175558916 (-)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000012170
 protein coding gene Chr1:174398950-174415681 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ ENSMUSG00225004669
 protein coding gene Chr1:178717004-178733260 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010046656
 protein coding gene Chr1:173395801-173412355 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MNDA, myeloid cell nuclear differentiation antigen
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MNDA, myeloid cell nuclear differentiation antigen
  • Synonyms
    PYHIN3
  • Links
    NCBI Gene ID: 4332
    UniProt: P41218

  • Chr Location
    1q23.1; chr1:158831332-158849506 (+)  GRCh38
  • Human Ortholog
    PYHIN1, pyrin and HIN domain family member 1
  • Synonyms
    IFIX
  • Links
    NCBI Gene ID: 149628
    UniProt: Q6K0P9

  • Chr Location
    1q23.1; chr1:158930796-158990870 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    700
  • Tissues
    96
  • cDNA Data
    30
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026536 Ensembl Gene Model | MGI Sequence Detail 16702 C57BL/6J ±  kb
transcript ENSMUST00000009340 Ensembl | MGI Sequence Detail 1785 Not Applicable  
polypeptide ENSMUSP00000009340 Ensembl | MGI Sequence Detail 425 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    Genomic 1
    cDNA 32
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:8394 Samanta H, et al., Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. J Biol Chem. 1986 Sep 5;261(25):11849-58
  • Latest
    J:359312 Jena KK, et al., Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair. Cell. 2024 Nov 4;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory