Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable double-stranded DNA binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in activation of innate immune response and cellular response to interferon-beta. Predicted to be located in nuclear periphery and nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; nucleolus; and nucleoplasm. Is expressed in adrenal gland; gland; hemolymphoid system; and thymus primordium. Orthologous to several human genes including IFI16 (interferon gamma inducible protein 16).