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Hykk Gene Detail
Summary
  • Symbol
    Hykk
  • Name
    hydroxylysine kinase 1
  • Synonyms
    Agphd1, C630028N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443139
    NCBI Gene: 235386
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54824574-54857208 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    768 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443139
 protein coding gene Chr9:54824567-54857208 (+)
129S1/SvImJ ENSMUSG00200034873
 protein coding gene Chr9:51951752-51984422 (+)
A/J ENSMUSG00195039779
 protein coding gene Chr9:51650160-51682806 (+)
AKR/J ENSMUSG00220030426
 protein coding gene Chr9:51783067-51815712 (+)
BALB/cJ ENSMUSG00180016236
 protein coding gene Chr9:51763514-51796162 (+)
C3H/HeJ ENSMUSG00175020749
 protein coding gene Chr9:51775324-51807966 (+)
C57BL/6NJ ENSMUSG00215024351
 protein coding gene Chr9:51748653-51781299 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032236
 protein coding gene Chr9:51678079-51704671 (+)
CAST/EiJ ENSTCUG00005020866
 protein coding gene Chr9:51684917-51717670 (+)
CBA/J ENSMUSG00210035320
 protein coding gene Chr9:51878235-51910913 (+)
DBA/2J ENSMUSG00185037956
 protein coding gene Chr9:51907700-51940367 (+)
FVB/NJ ENSMUSG00205034174
 protein coding gene Chr9:52186030-52220494 (+)
JF1/MsJ ENSUMUG00000045514
 protein coding gene Chr9:51916427-51942948 (+)
LP/J ENSMUSG00230034070
 protein coding gene Chr9:52151725-52184396 (+)
NOD/ShiLtJ ENSMUSG00190038951
 protein coding gene Chr9:51965680-51998326 (+)
NZO/HlLtJ ENSMUSG00225027815
 protein coding gene Chr9:52173383-52206037 (+)
PWK/PhJ ENSLUMG00010038129
 protein coding gene Chr9:51879161-51905831 (+)
SPRET/EiJ ENSMSPG00010022887
 protein coding gene Chr9:52889540-52911929 (+)
WSB/EiJ ENSIUOG00005037496
 protein coding gene Chr9:51376372-51409024 (+)



Homology
more
  • Human Ortholog
    HYKK, hydroxylysine kinase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HYKK, hydroxylysine kinase
  • Synonyms
    AGPHD1
  • Links
    NCBI Gene ID: 123688
    UniProt: A2RU49

  • Chr Location
    15q25.1; chr15:78507564-78537373 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human HYKK associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    29
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 235386 NCBI Gene Model | MGI Sequence Detail 32635 C57BL/6J ±  kb
transcript NM_177351 RefSeq | MGI Sequence Detail 5103 C57BL/6  
polypeptide Q5U5V2 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:383044 Veiga-da-Cunha M, et al., Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. J Biol Chem. 2012 Mar 2;287(10):7246-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory