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Purb Gene Detail
Summary
  • Symbol
    Purb
  • Name
    purine rich element binding protein B
  • Synonyms
    2310015K15Rik, Cager-2, D11Bwg0414e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338779
    NCBI Gene: 19291
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6417599-6425917 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 4.16 cM, cytoband A1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    118 from dbSNP Build 142
  • Strain Annotations
    21
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338779
 protein coding gene Chr11:6417599-6426076 (-)
129S1/SvImJ ENSMUSG00200032520
 protein coding gene Chr11:3359553-3367871 (-)
A/J ENSMUSG00195020734
 protein coding gene Chr11:3281421-3289740 (-)
AKR/J ENSMUSG00220007655
 protein coding gene Chr11:3310742-3319061 (-)
BALB/cJ ENSMUSG00180022491
 protein coding gene Chr11:3308013-3395726 (-)
BALB/cJ ENSMUSG00180022506
 protein coding gene Chr11:3311018-3316410 (-)
C3H/HeJ ENSMUSG00175009763
 protein coding gene Chr11:3286189-3294505 (-)
C57BL/6NJ ENSMUSG00215019226
 protein coding gene Chr11:3306953-3315271 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016075
 protein coding gene Chr11:3318317-3326615 (-)
CAST/EiJ ENSTCUG00005035104
 protein coding gene Chr11:3368001-3376321 (-)
CBA/J ENSMUSG00210017912
 protein coding gene Chr11:3295948-3304266 (-)
DBA/2J ENSMUSG00185016771
 protein coding gene Chr11:3393730-3402048 (-)
FVB/NJ ENSMUSG00205018149
 protein coding gene Chr11:3266970-3275288 (-)
JF1/MsJ ENSUMUG00000021041
 protein coding gene Chr11:3534755-3543068 (-)
LP/J ENSMUSG00230029030
 protein coding gene Chr11:4463263-4468655 (-)
LP/J ENSMUSG00230028987
 protein coding gene Chr11:4460258-4547963 (-)
NOD/ShiLtJ ENSMUSG00190038491
 protein coding gene Chr11:3273917-3282236 (-)
NZO/HlLtJ ENSMUSG00225024988
 protein coding gene Chr11:6498594-6506912 (-)
PWK/PhJ ENSLUMG00010018283
 protein coding gene Chr11:3286952-3295271 (-)
SPRET/EiJ ENSMSPG00010007863
 protein coding gene Chr11:3339051-3347370 (-)
WSB/EiJ ENSIUOG00005006805
 protein coding gene Chr11:3298903-3307201 (-)



Homology
more
  • Human Ortholog
    PURB, purine rich element binding protein B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PURB, purine rich element binding protein B
  • Synonyms
    PURBETA
  • Links
    NCBI Gene ID: 5814
    UniProt: Q96QR8

  • Chr Location
    7p13; chr7:44876299-44885530 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    46
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    2
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000094483 Ensembl Gene Model | MGI Sequence Detail 8319 C57BL/6J ±  kb
transcript ENSMUST00000179343 Ensembl | MGI Sequence Detail 8319 Not Applicable  
polypeptide ENSMUSP00000136957 Ensembl | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013495 transcriptional regulator protein Pur-beta
    (term hierarchy)
  • InterPro Domains
    IPR006628 Purine-rich element binding protein family
  • GlyGen
    O35295 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 14
    Primer pair 2
    Antibodies 1

    Microarray probesets 10
Other
Accession IDs
less
MGD-MRK-34063, MGI:106370, MGI:1923687, MGI:3034759
References
more
  • Summaries
    All 55
    Developmental Gene Expression 4
    Gene Ontology 16
    Phenotypes 1
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:368627 Gather F, et al., The lincRNA Pantr1 is a FOXG1 target gene conferring site-specific chromatin binding of FOXG1. Nucleic Acids Res. 2025 Jun 20;53(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory