Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; SMAD binding activity; and nucleic acid binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in heart and hindlimb muscle. Orthologous to human PURB (purine rich element binding protein B).