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Nsg1 Gene Detail
Summary
  • Symbol
    Nsg1
  • Name
    neuron specific gene family member 1
  • Synonyms
    m234, NEEP21, p21
  • Feature Type
    protein coding gene
  • IDs
    MGI:109149
    NCBI Gene: 18196
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:38294537-38317087 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 20.21 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    620 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109149
 protein coding gene Chr5:38294536-38317251 (-)
129S1/SvImJ ENSMUSG00200029143
 protein coding gene Chr5:33744463-33766633 (-)
A/J ENSMUSG00195028015
 protein coding gene Chr5:33201394-33223586 (-)
AKR/J ENSMUSG00220002193
 protein coding gene Chr5:33228170-33250359 (-)
BALB/cJ ENSMUSG00180022562
 protein coding gene Chr5:33004204-33026394 (-)
C3H/HeJ ENSMUSG00175018917
 protein coding gene Chr5:34988330-35010519 (-)
C57BL/6NJ ENSMUSG00215004952
 protein coding gene Chr5:33743025-33765194 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027175
 protein coding gene Chr5:32997273-33018923 (-)
CAST/EiJ ENSTCUG00005022795
 protein coding gene Chr5:33203557-33225746 (-)
CBA/J ENSMUSG00210003550
 protein coding gene Chr5:33950305-33972494 (-)
DBA/2J ENSMUSG00185017172
 protein coding gene Chr5:35828487-35850657 (-)
FVB/NJ ENSMUSG00205014341
 protein coding gene Chr5:32710900-32733071 (-)
JF1/MsJ ENSUMUG00000001431
 protein coding gene Chr5:40403229-40425368 (-)
LP/J ENSMUSG00230002374
 protein coding gene Chr5:40471531-40493701 (-)
NOD/ShiLtJ ENSMUSG00190002844
 protein coding gene Chr5:33015465-33037635 (-)
NZO/HlLtJ ENSMUSG00225016287
 protein coding gene Chr5:45622645-45644825 (-)
PWK/PhJ ENSLUMG00010020727
 protein coding gene Chr5:33080239-33102377 (-)
SPRET/EiJ ENSMSPG00010033700
 protein coding gene Chr5:34323981-34346722 (-)
WSB/EiJ ENSIUOG00005016773
 protein coding gene Chr5:35911004-35933192 (-)



Homology
more
  • Human Ortholog
    NSG1, neuronal vesicle trafficking associated 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NSG1, neuronal vesicle trafficking associated 1
  • Synonyms
    D4S234, D4S234E, NEEP21, P21
  • Links
    NCBI Gene ID: 27065
    UniProt: P42857

  • Chr Location
    4p16.3; chr4:4348140-4419058 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    100
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    64
  • cDNA Data
    100
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 18196 NCBI Gene Model | MGI Sequence Detail 22551 C57BL/6J ±  kb
    transcript NM_001359090 RefSeq | MGI Sequence Detail 2775 ZRU/MplStud  
    polypeptide Q62092 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000059767 neuronal vesicle trafficking-associated protein 1
      (term hierarchy)
    • InterPro Domains
      IPR009431 Neuronal vesicle trafficking-associated protein
    Molecular
    Reagents
    less
    • All nucleic 104
      Genomic 1
      cDNA 100
      Primer pair 1
      Other 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-38193
    References
    more
    • Summaries
      All 74
      Developmental Gene Expression 11
      Diseases 1
      Gene Ontology 13
      Phenotypes 28
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory