Sequence Detail

ID/Version

Q62092 O54717 Q3UF63 Q922E5 (UniProt | EBI)

Last sequence update: 2002-05-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Neuronal vesicle trafficking-associated protein 1 {ECO:0000250|UniProtKB:P42857};AltName: Full=M234;AltName: Full=Neuron-enriched endosomal protein of 21 kDa {ECO:0000303|PubMed:15187090};AltName: Full=Neuron-specific protein family member 1

Provider

SWISS-PROT

Sequence

Polypeptide 185 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nsg1	neuron specific gene family member 1	56	104	2	10

Sequence references in MGI

J:37687 Carlock L, et al., Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons. Brain Res Mol Brain Res. 1996 Dec;42(2):202-12
J:45799 Saberan-Djoneidi D, et al., A 21-kDa polypeptide belonging to a new family of proteins is expressed in the Golgi apparatus of neural and germ cells. J Biol Chem. 1998 Feb 13;273(7):3909-14
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166440 Norstrom EM, et al., Identification of NEEP21 as a ss-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro. J Neurosci. 2010 Nov 17;30(46):15677-85
J:238465 Steiner P, et al., Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. EMBO J. 2005 Aug 17;24(16):2873-84
J:242500 Barford K, et al., The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. J Comp Neurol. 2017 Jun 01;525(8):1861-1878
J:248439 Debaigt C, et al., Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors. J Biol Chem. 2004 Aug 20;279(34):35687-91
J:248442 Yap CC, et al., The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. Sci Rep. 2017 Sep 5;7(1):10481
J:248466 Steiner P, et al., Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD. J Cell Biol. 2002 Jun 24;157(7):1197-209
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89