Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  1
• Reference
  J:9342 Seldin MF, et al., A molecular genetic approach to gld autoimmune disease. Curr Top Microbiol Immunol. 1988;137:227-32
• ID
  MGI:39529

Genes

Gene	Allele	Assay Type	Description
Cfh		Southern analysis	pMH8
C4bp		Southern analysis	pMBP.15
Ren1		Southern analysis	Id-2
Ren2		Southern analysis	Id-2
Ptprc		Southern analysis	pLy-5-68
Serpinc1		Southern analysis	pAt3
Fasl	Fasl^gld	visible phenotype	lymphadenopathy + Ig levels
Fcgr3		Southern analysis	J774
Apoa2		Southern analysis	mouse cDNA
Spta1		Southern analysis	pMaSp1

Notes

• Reference
  Revised gene symbols: Ptprc, Fcgr2 (formerly Cd45, Ly-17 respectively).
• Experiment
  Based on the analysis of 95 backcross mice from (C3H-gld/gld x M. spretus)F1 x C3H-gld/gld matings and 7 sets of RI lines, 9 genes were assigned to Chromosome 1 in the following order: Centromere - - Cfh - C4bp - Ren1 - Ren2 - Ptprc - Serpinc1 - Fasl - Fcgr2 - Apoa2 - Spna1. Supporting data is reported elsewhere.