Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Trp53
transformation related protein 53
MGI:98834

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Click on allele symbol for full phenotype details.

	Caption: Skin hyperpigmentation in Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice but not in Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm1Brn/Trp53^tm1Brn Tg(KRT14-cre/ERT)20Efu/0 mice (details) Represented Alleles: Csnk1a1^tm1.1Ybn, casein kinase 1, alpha 1; targeted mutation 1.1, Yinon Ben-Neriah Tg(KRT14-cre/ERT)20Efu, transgene insertion 20, Elaine Fuchs Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Chang CH, Proc Natl Acad Sci U S A 2017 Sep 19;114(38):E8035-E8044. Copyright 2017 National Academy of Sciences, U.S.A. J:253611
	Caption: Increased apoptosis in the developing central nervous system of Rps7^Zma/Rps7⁺ embryos which is reduced in Rps7^Zma/Rps7⁺ Trp53^tm1Tyj/Trp53⁺ embryos (details) Represented Alleles: Rps7^Zma, ribosomal protein S7; zuma Trp53^tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks Copyright: This image is from Watkins-Chow DE, PLoS Genet 2013 Jan;9(1):e1003094, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195156
	Caption: Embryonic developmental delay in Rps7^Zma/Rps7⁺ mice is suppressed by Trp53 deficiency (details) Represented Alleles: Rps7^Zma, ribosomal protein S7; zuma Trp53^tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks Copyright: This image is from Watkins-Chow DE, PLoS Genet 2013 Jan;9(1):e1003094, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195156
	Caption: Trp53^tm1Yjc/Trp53^tm1Yjc mice develop B cell lymphomas (details) Represented Alleles: Trp53^tm1Yjc, transformation related protein 53; targeted mutation 1, Y Jeffrey Chiang Copyright: This image is from Chiang YJ, PLoS One 2012;7(11):e49305, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195018
	Caption: Tg(Ly6e-MALT1)#Isg/0 Trp53^tm1Tyj/Trp53^tm1Tyj mice develop activated B-cell diffuse large-cell lymphoma (details) Represented Alleles: Tg(Ly6e-MALT1)#Isg, transgene insertion, Isidro Sanchez-Garcia Trp53^tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks Copyright: This image is from Vicente-Duenas C, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):10534-9. Copyright 2012 National Academy of Sciences, U.S.A. J:185590
	Caption: Characterization of lmphomas in Tg(Ly6e-MALT1)#Isg/0 Trp53^tm1Tyj/Trp53^tm1Tyj mice (details) Represented Alleles: Tg(Ly6e-MALT1)#Isg, transgene insertion, Isidro Sanchez-Garcia Trp53^tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks Copyright: This image is from Vicente-Duenas C, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):10534-9. Copyright 2012 National Academy of Sciences, U.S.A. J:185590
	Caption: The embryonic lethality of Cops6^{Gt(RRI087)Byg}/Cops6^{Gt(RRI087)Byg} mice can be partially rescued by concomitant loss of Trp53 (details) Represented Alleles: Cops6^{Gt(RRI087)Byg}, COP9 signalosome subunit 6; gene trap RRI087, BayGenomics Trp53^tm1Glo, transformation related protein 53; targeted mutation 1, Guillermina Lozano Copyright: This image is from Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172038
	Caption: Ing2^tm1.1Ccha/Ing2^tm1.1Ccha and Trp53^tm1Brd/Trp53^tm1Brd Ing2^tm1.1Ccha/Ing2^tm1.1Ccha mice exhibit increased testicular apoptosis and decreased testis weight (details) Represented Alleles: Ing2^tm1.1Ccha, inhibitor of growth family, member 2; targeted mutation 1.1, Curtis C Harri Trp53^tm1Brd, transformation related protein 53; targeted mutation 1, Allan Bradley Copyright: This image is from Saito M, PLoS One 2010;5(11):e15541, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:167311
	Caption: High-grade prostate intraepithelial neoplasia in Brca2^tm1Brn/Brca2^tm1Brn Tg(Pbsn-cre)4Prb/0 Trp53^tm1Brn/Trp53^tm1Brn and prostate hyperplasia and intraepithelial neoplasia in Brca2^tm1Brn/Brca2^tm1Brn Trp53^tm1Brn/Trp53⁺ Tg(Pbsn-cre)4Prb/0 mice (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511
	Caption: Increased DNA damage and apoptosis in prostates of various prostate-specific conditional Brca2^tm1Brn and double Brca2^tm1Brn and Trp53^tm1Brn mutants (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511

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