Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Gcn1
GCN1 activator of EIF2AK4
MGI:2444248

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Click on allele symbol for full phenotype details.

	Caption: Gcn1^em1(IMPC)J/Gcn1^em1(IMPC)J embryos are small and growth delayed. E9.5 embryos remain unturned or display incomplete turning, show abnormal yolk sac vascularization, and abnormal head shape and cranial neural tube closure. E10.5 embryos display turning defects, severe cardiac defects, open cranial neural tube and more than 50% lethality. (details) Represented Alleles: Gcn1^em1(IMPC)J, GCN1 activator of EIF2AK4; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Placental abnormalities in Gcn1^em1(IMPC)J/Gcn1^em1(IMPC)J embryos, with impaired chorioallantoic attachment and branching and multiple labyrinth zone defects. (details) Represented Alleles: Gcn1^em1(IMPC)J, GCN1 activator of EIF2AK4; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E8.5 Gcn1^em1(IMPC)J/Gcn1^em1(IMPC)J embryos show embryonic growth delay despite formation of all 3 germ layers. (details) Represented Alleles: Gcn1^em1(IMPC)J, GCN1 activator of EIF2AK4; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Although grossly abnormal, Gcn1^em1(IMPC)J/Gcn1^em1(IMPC)J embryos form all 3 germ layers and initiate cardiac development and gut tube closure at E9.5. (details) Represented Alleles: Gcn1^em1(IMPC)J, GCN1 activator of EIF2AK4; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E7.5 Gcn1^em1(IMPC)J/Gcn1^em1(IMPC)J (-/-) embryos are always the smallest in their litters. (details) Represented Alleles: Gcn1^em1(IMPC)J, GCN1 activator of EIF2AK4; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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