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Phenotype Images associated with this Gene
Symbol
Name
ID
Gjc2
gap junction protein, gamma 2
MGI:2153060


4 phenotype image(s) for Gjc2 alleles
Showing image(s) 1 to 4

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Click on allele symbol for full phenotype details.

Caption: Toluidine blue/pyronin g stained semi-thin sections reveal cystic spaces in white matter of Gjc2tm2.1Kwi/Gjc2tm2.1Kwi mice (details)
Represented Alleles:
Gjc2tm2.1Kwi, gap junction protein, gamma 2; targeted mutation 2.1, Klaus Willecke
Copyright: This image is from Tress O, PLoS Genet 2011 Jul;7(7):e1002146, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174197
Caption: Disturbed myelin basic protein (MBP) expression accompanied by astrogliosis and microglial activation in juvenile Gjc2tm2.1Kwi/Gjc2tm2.1Kwi, Gjc2tm2.1Kwi/Gjc2+, and Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi mice (details)
Represented Alleles:
Gjc2tm1(EGFP)Kwi, gap junction protein, gamma 2; targeted mutation 1, Klaus Willecke
Gjc2tm2.1Kwi, gap junction protein, gamma 2; targeted mutation 2.1, Klaus Willecke
Copyright: This image is from Tress O, PLoS Genet 2011 Jul;7(7):e1002146, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174197
Caption: Insufficient myelination resulting from loss of Gjc2 (Cx47) function is largely compensated in adult Gjc2tm2.1Kwi/Gjc2+ and Gjc2tm2.1Kwi/Gjc2tm2.1Kwi mice (details)
Represented Alleles:
Gjb1tm1Kwi, gap junction protein, beta 1; targeted mutation 1, Klaus Willecke
Gjc2tm2.1Kwi, gap junction protein, gamma 2; targeted mutation 2.1, Klaus Willecke
Copyright: This image is from Tress O, PLoS Genet 2011 Jul;7(7):e1002146, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174197
Caption: A variable number of blood vessels predominantly in the hippocampal region of Gjc2tm2.1Kwi/Gjc2tm2.1Kwi mice feature perivascular glia being filled with basophilic material or undergoing conspicuous destruction (details)
Represented Alleles:
Gjc2tm2.1Kwi, gap junction protein, gamma 2; targeted mutation 2.1, Klaus Willecke
Copyright: This image is from Tress O, PLoS Genet 2011 Jul;7(7):e1002146, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174197

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory